Apoptotic cell-derived extracellular vesicles: structure-function relationships.
Biochem Soc Trans
; 47(2): 509-516, 2019 04 30.
Article
em En
| MEDLINE
| ID: mdl-30952802
ABSTRACT
Apoptosis is an essential process for normal physiology and plays a key role in the resolution of inflammation. Clearance of apoptotic cells (ACs) involves complex signalling between phagocytic cells, ACs, and the extracellular vesicles (EVs) they produce. Here, we discuss apoptotic cell-derived extracellular vesicles (ACdEVs) and how their structure relates to their function in AC clearance and the control of inflammation, focussing on the ACdEV proteome. We review the current knowledge, ongoing work and future directions for research in this field.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Apoptose
/
Vesículas Extracelulares
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Biochem Soc Trans
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Reino Unido