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The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/ß-catenin-TCF1-CYP2E1 signaling pathway.
Xu, Ying; Chen, Dan; Lin, Xiu-Xian; Zhao, Qing; Guo, Jing; Chen, Li-Jie; Zhang, Wei; Xiao, Jian; Lian, Guang-Hui; Peng, Shi-Fang; Guo, Dong; Yang, Hong; Obianom, Obinna; Shu, Yan; Chen, Yao.
Afiliação
  • Xu Y; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
  • Chen D; Institute of Clinical Pharmacology, Central South University, Changsha, 410078, Hunan, China.
  • Lin XX; Engineering Research Center of Applied Technology of Pharmacogenomics, Ministry of Education, 110 Xiangya Road, Changsha, 410078, People's Republic of China.
  • Zhao Q; National Clinical Research Center for Geriatric Disorders, 87 Xiangya Road, Changsha, 410008, Hunan, People's Republic of China.
  • Guo J; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
  • Chen LJ; Institute of Clinical Pharmacology, Central South University, Changsha, 410078, Hunan, China.
  • Zhang W; Engineering Research Center of Applied Technology of Pharmacogenomics, Ministry of Education, 110 Xiangya Road, Changsha, 410078, People's Republic of China.
  • Xiao J; National Clinical Research Center for Geriatric Disorders, 87 Xiangya Road, Changsha, 410008, Hunan, People's Republic of China.
  • Lian GH; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
  • Peng SF; Institute of Clinical Pharmacology, Central South University, Changsha, 410078, Hunan, China.
  • Guo D; Engineering Research Center of Applied Technology of Pharmacogenomics, Ministry of Education, 110 Xiangya Road, Changsha, 410078, People's Republic of China.
  • Yang H; National Clinical Research Center for Geriatric Disorders, 87 Xiangya Road, Changsha, 410008, Hunan, People's Republic of China.
  • Obianom O; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
  • Shu Y; Institute of Clinical Pharmacology, Central South University, Changsha, 410078, Hunan, China.
  • Chen Y; Engineering Research Center of Applied Technology of Pharmacogenomics, Ministry of Education, 110 Xiangya Road, Changsha, 410078, People's Republic of China.
Arch Toxicol ; 93(6): 1679-1695, 2019 06.
Article em En | MEDLINE | ID: mdl-30976847
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP2E1 / Beta Catenina / Fator 1-alfa Nuclear de Hepatócito / Proteína-6 Relacionada a Receptor de Lipoproteína de Baixa Densidade / Via de Sinalização Wnt / Hepatite Alcoólica Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Arch Toxicol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP2E1 / Beta Catenina / Fator 1-alfa Nuclear de Hepatócito / Proteína-6 Relacionada a Receptor de Lipoproteína de Baixa Densidade / Via de Sinalização Wnt / Hepatite Alcoólica Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Arch Toxicol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China