[Early determinants of chronic obstructive pulmonary disease: Lung regeneration, a new therapeutic target?] / Déterminants précoces de la bronchopneumopathie chronique obstructive : la régénération pulmonaire, une nouvelle piste thérapeutique ?
Rev Mal Respir
; 36(4): 447-450, 2019 Apr.
Article
em Fr
| MEDLINE
| ID: mdl-31010755
ABSTRACT
Chronic obstructive pulmonary disease, a disease of increasing incidence, is related mainly to smoking. Although symptoms only appear at adulthood, the disease can develop from early life events. For example, bronchopulmonary dysplasia, which occurs in preterm infants, is characterized by airspace enlargement and could lead to late lung consequences. Once the lesions are established, no curative treatment is available. Stimulating lung regeneration from endogenous stem cells is therefore an exciting research domain, particularly through the activation of the mesenchymal contingent located in the lung stem cell niche.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Regeneração
/
Doença Pulmonar Obstrutiva Crônica
/
Suscetibilidade a Doenças
/
Pulmão
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
/
Newborn
Idioma:
Fr
Revista:
Rev Mal Respir
Ano de publicação:
2019
Tipo de documento:
Article