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Identification of a small-molecule compound that inhibits homodimerization of oncogenic NAC1 protein and sensitizes cancer cells to anticancer agents.
Wang, XiaoHui; Ji, Cheng; Zhang, HongHan; Shan, Yu; Ren, YiJie; Hu, YanWei; Shi, LiangRong; Guo, LingChuan; Zhu, WeiDong; Xia, YuJuan; Liu, BeiJia; Rong, ZiYun; Wu, BiLian; Ming, ZhiJun; Ren, XingCong; Song, JianXun; Yang, JinMing; Zhang, Yi.
Afiliação
  • Wang X; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Ji C; Department of Respiratory Medicine, First Affiliated Hospital, Soochow University, 215000 Suzhou, Jiangsu, China.
  • Zhang H; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Shan Y; Institute of Botany, Jiangsu Province and Chinese Academy of Science, 210014 Nanjing, Jiangsu, China.
  • Ren Y; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Hu Y; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Shi L; Radiological Intervention Center, Department of Radiology, Xiangya Hospital, Central South University, 410013 Changsha, Hunan, China.
  • Guo L; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Zhu W; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Xia Y; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Liu B; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Rong Z; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Wu B; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Ming Z; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China.
  • Ren X; Department of Cancer Biology and Toxicology, Markey Cancer Center, University of Kentucky College of Medicine, Lexington, Kentucky 40506.
  • Song J; Department of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, College Station, Texas 77843, and.
  • Yang J; Department of Cancer Biology and Toxicology, Markey Cancer Center, University of Kentucky College of Medicine, Lexington, Kentucky 40506 jyang@uky.edu.
  • Zhang Y; From the Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 215123 Suzhou, Jiangsu, China, zhangyi@suda.edu.cn.
J Biol Chem ; 294(25): 10006-10017, 2019 06 21.
Article em En | MEDLINE | ID: mdl-31101655
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Compostos de Bifenilo / Neoplasias da Mama / Resistencia a Medicamentos Antineoplásicos / Bibliotecas de Moléculas Pequenas / Multimerização Proteica / Acetamidas / Proteínas de Neoplasias / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Compostos de Bifenilo / Neoplasias da Mama / Resistencia a Medicamentos Antineoplásicos / Bibliotecas de Moléculas Pequenas / Multimerização Proteica / Acetamidas / Proteínas de Neoplasias / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China