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Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE).
Caprio, M; Infante, M; Moriconi, E; Armani, A; Fabbri, A; Mantovani, G; Mariani, S; Lubrano, C; Poggiogalle, E; Migliaccio, S; Donini, L M; Basciani, S; Cignarelli, A; Conte, E; Ceccarini, G; Bogazzi, F; Cimino, L; Condorelli, R A; La Vignera, S; Calogero, A E; Gambineri, A; Vignozzi, L; Prodam, F; Aimaretti, G; Linsalata, G; Buralli, S; Monzani, F; Aversa, A; Vettor, R; Santini, F; Vitti, P; Gnessi, L; Pagotto, U; Giorgino, F; Colao, A; Lenzi, A.
Afiliação
  • Caprio M; Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele Pisana, Via di Val Cannuta 247, 00166, Rome, Italy. massimiliano.caprio@sanraffaele.it.
  • Infante M; Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Rome, Italy. massimiliano.caprio@sanraffaele.it.
  • Moriconi E; Unit of Endocrinology and Metabolic Diseases, Department of Systems Medicine, CTO A. Alesini Hospital, ASL Roma 2, University of Rome Tor Vergata, Rome, Italy.
  • Armani A; Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele Pisana, Via di Val Cannuta 247, 00166, Rome, Italy.
  • Fabbri A; Section of Medical Pathophysiology, Food Science and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  • Mantovani G; Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele Pisana, Via di Val Cannuta 247, 00166, Rome, Italy.
  • Mariani S; Unit of Endocrinology and Metabolic Diseases, Department of Systems Medicine, CTO A. Alesini Hospital, ASL Roma 2, University of Rome Tor Vergata, Rome, Italy.
  • Lubrano C; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Endocrinology and Diabetology Unit, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
  • Poggiogalle E; Section of Medical Pathophysiology, Food Science and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  • Migliaccio S; Section of Medical Pathophysiology, Food Science and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  • Donini LM; Section of Medical Pathophysiology, Food Science and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  • Basciani S; Section of Health Sciences, Department of Movement, Human and Health Sciences, "Foro Italico" University of Rome, Rome, Italy.
  • Cignarelli A; Section of Medical Pathophysiology, Food Science and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  • Conte E; Section of Medical Pathophysiology, Food Science and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  • Ceccarini G; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy.
  • Bogazzi F; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy.
  • Cimino L; Endocrinology Unit, Obesity and Lipodystrophy Center, University Hospital of Pisa, Pisa, Italy.
  • Condorelli RA; Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • La Vignera S; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
  • Calogero AE; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
  • Gambineri A; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
  • Vignozzi L; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
  • Prodam F; Endocrinology Unit and Center for Applied Biomedical Research, Department of Medical and Surgical Sciences, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy.
  • Aimaretti G; Andrology, Women's Endocrinology and Gender Incongruence Unit, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, AOU Careggi, Florence, Italy.
  • Linsalata G; Endocrinology, Department of Translational Medicine and Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
  • Buralli S; Endocrinology, Department of Translational Medicine and Department of Health Sciences, University of Piemonte Orientale, Novara, Italy.
  • Monzani F; Geriatrics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Aversa A; Geriatrics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Vettor R; Geriatrics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Santini F; Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Catanzaro, Italy.
  • Vitti P; Department of Medicine, Internal Medicine 3, University Hospital of Padova, Padua, Italy.
  • Gnessi L; Endocrinology Unit, Obesity and Lipodystrophy Center, University Hospital of Pisa, Pisa, Italy.
  • Pagotto U; Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Giorgino F; Section of Medical Pathophysiology, Food Science and Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  • Colao A; Endocrinology Unit and Center for Applied Biomedical Research, Department of Medical and Surgical Sciences, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy.
  • Lenzi A; Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy.
J Endocrinol Invest ; 42(11): 1365-1386, 2019 Nov.
Article em En | MEDLINE | ID: mdl-31111407
ABSTRACT

BACKGROUND:

Weight loss is a milestone in the prevention of chronic diseases associated with high morbility and mortality in industrialized countries. Very-low calorie ketogenic diets (VLCKDs) are increasingly used in clinical practice for weight loss and management of obesity-related comorbidities. Despite evidence on the clinical benefits of VLCKDs is rapidly emerging, some concern still exists about their potential risks and their use in the long-term, due to paucity of clinical studies. Notably, there is an important lack of guidelines on this topic, and the use and implementation of VLCKDs occurs vastly in the absence of clear evidence-based indications.

PURPOSE:

We describe here the biochemistry, benefits and risks of VLCKDs, and provide recommendations on the correct use of this therapeutic approach for weight loss and management of metabolic diseases at different stages of life.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dieta Redutora / Endocrinologia / Dieta Cetogênica / Doenças Metabólicas / Obesidade Tipo de estudo: Guideline / Systematic_reviews Limite: Humans Idioma: En Revista: J Endocrinol Invest Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dieta Redutora / Endocrinologia / Dieta Cetogênica / Doenças Metabólicas / Obesidade Tipo de estudo: Guideline / Systematic_reviews Limite: Humans Idioma: En Revista: J Endocrinol Invest Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália