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Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemotherapy alone as first-line treatment for metastatic non-squamous non-small-cell lung cancer (IMpower130): a multicentre, randomised, open-label, phase 3 trial.
West, Howard; McCleod, Michael; Hussein, Maen; Morabito, Alessandro; Rittmeyer, Achim; Conter, Henry J; Kopp, Hans-Georg; Daniel, Davey; McCune, Steven; Mekhail, Tarek; Zer, Alona; Reinmuth, Niels; Sadiq, Ahad; Sandler, Alan; Lin, Wei; Ochi Lohmann, Tania; Archer, Venice; Wang, Lijia; Kowanetz, Marcin; Cappuzzo, Federico.
Afiliação
  • West H; Thoracic Oncology Program, Swedish Cancer Institute, Seattle, WA, USA.
  • McCleod M; Sarah Cannon Research Institute, Florida Cancer Specialists, Fort Myers, FL, USA.
  • Hussein M; Sarah Cannon Research Institute, Florida Cancer Specialists, Leesburg, FL, USA.
  • Morabito A; Thoracic Medical Oncology, National Cancer Institute, IRCCS Fondazione G. Pascale, Napoli, Italy.
  • Rittmeyer A; Department of Thoracic Oncology, Lungenfachklinik Immenhausen, Immenhausen, Germany.
  • Conter HJ; Department of Medicine, William Osler Health System, Brampton, ON, Canada.
  • Kopp HG; Robert Bosch Centrum für Tumorerkrankungen, Klinik Schillerhöhe, Stuttgart, Germany.
  • Daniel D; Tennessee Oncology, Chattanooga, TN, USA.
  • McCune S; Northwest Georgia Oncology Centers, Marietta, GA, USA.
  • Mekhail T; Florida Hospital Cancer Institute, Orlando, FL, USA.
  • Zer A; Thoracic Oncology Unit, Rabin Medical Center, Tel Aviv University, Petah-Tikva, Israel.
  • Reinmuth N; Thoracic Oncology, Asklepios Clinics Munich-Gauting, Gauting, Germany.
  • Sadiq A; Fort Wayne Medical Oncology and Hematology, Fort Wayne, IN, USA.
  • Sandler A; Clinical Science, Genentech, South San Francisco, CA, USA.
  • Lin W; Clinical Science, Genentech, South San Francisco, CA, USA; Nektar Therapeutics, San Francisco, CA, USA.
  • Ochi Lohmann T; PD Oncology, F. Hoffmann-La Roche, Basel, Switzerland.
  • Archer V; PD Oncology, Roche Products, Welwyn Garden City, UK.
  • Wang L; Biostatistics, Genentech, South San Francisco, CA, USA.
  • Kowanetz M; Oncology Biomarker Development, Genentech, South San Francisco, CA, USA; Biotherapeutics, Inc., Redwood City, CA, USA.
  • Cappuzzo F; Department of Oncology and Hematology, AUSL Romagna, Ravenna, Italy. Electronic address: f.cappuzzo@gmail.com.
Lancet Oncol ; 20(7): 924-937, 2019 07.
Article em En | MEDLINE | ID: mdl-31122901
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Carboplatina / Paclitaxel / Carcinoma Pulmonar de Células não Pequenas / Albuminas / Anticorpos Monoclonais Humanizados / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Carboplatina / Paclitaxel / Carcinoma Pulmonar de Células não Pequenas / Albuminas / Anticorpos Monoclonais Humanizados / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos