Accumulation of Progerin Affects the Symmetry of Cell Division and Is Associated with Impaired Wnt Signaling and the Mislocalization of Nuclear Envelope Proteins.

Sola-Carvajal, Agustín; Revêchon, Gwladys; Helgadottir, Hafdis T; Whisenant, Daniel; Hagblom, Robin; Döhla, Julia; Katajisto, Pekka; Brodin, David; Fagerström-Billai, Fredrik; Viceconte, Nikenza; Eriksson, Maria

Sola-Carvajal, Agustín; Revêchon, Gwladys; Helgadottir, Hafdis T; Whisenant, Daniel; Hagblom, Robin; Döhla, Julia; Katajisto, Pekka; Brodin, David; Fagerström-Billai, Fredrik; Viceconte, Nikenza; Eriksson, Maria.

Afiliação

Sola-Carvajal A; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden. Electronic address: Agustin.Sola.Carvajal@ki.se.
Revêchon G; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
Helgadottir HT; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
Whisenant D; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
Hagblom R; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
Döhla J; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden; Institute of Biotechnology, University of Helsinki, Helsinki, Finland.
Katajisto P; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden; Institute of Biotechnology, University of Helsinki, Helsinki, Finland.
Brodin D; Bioinformatics and Expression Core Facility, Karolinska Institutet, Huddinge, Sweden.
Fagerström-Billai F; Bioinformatics and Expression Core Facility, Karolinska Institutet, Huddinge, Sweden.
Viceconte N; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
Eriksson M; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden. Electronic address: Maria.Eriksson.2@ki.se.

J Invest Dermatol ; 139(11): 2272-2280.e12, 2019 11.

Article em En | MEDLINE | ID: mdl-31128203

Assuntos

Núcleo Celular/metabolismo; Epiderme/fisiologia; Lamina Tipo A/genética; Progéria/metabolismo; Células-Tronco/fisiologia; beta Catenina/metabolismo; Animais; Divisão Celular; Células Cultivadas; Modelos Animais de Doenças; Humanos; Lamina Tipo A/metabolismo; Proteínas de Membrana/metabolismo; Camundongos; Camundongos Transgênicos; Proteínas do Tecido Nervoso/metabolismo; Membrana Nuclear/metabolismo; Proteínas Nucleares/metabolismo; Progéria/genética; Progéria/patologia; Transporte Proteico; Via de Sinalização Wnt

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Progéria / Células-Tronco / Núcleo Celular / Lamina Tipo A / Epiderme / Beta Catenina Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Invest Dermatol Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google