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Reduced burden of diabetes and improved quality of life: Experiences from unrestricted day-and-night hybrid closed-loop use in very young children with type 1 diabetes.
Musolino, Gianluca; Dovc, Klemen; Boughton, Charlotte K; Tauschmann, Martin; Allen, Janet M; Nagl, Katrin; Fritsch, Maria; Yong, James; Metcalfe, Emily; Schaeffer, Dominique; Fichelle, Muriel; Schierloh, Ulrike; Thiele, Alena G; Abt, Daniela; Kojzar, Harald; Mader, Julia K; Slegtenhorst, Sonja; Ashcroft, Nicole; Wilinska, Malgorzata E; Sibayan, Judy; Cohen, Nathan; Kollman, Craig; Hofer, Sabine E; Fröhlich-Reiterer, Elke; Kapellen, Thomas M; Acerini, Carlo L; de Beaufort, Carine; Campbell, Fiona; Rami-Merhar, Birgit; Hovorka, Roman.
Afiliação
  • Musolino G; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Dovc K; Department of Paediatric Endocrinology, Diabetes and Metabolic Diseases, University Children's Hospital, University Medical Centre, Ljubljana, Slovenia.
  • Boughton CK; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Tauschmann M; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Allen JM; Department of Paediatrics, University of Cambridge, Cambridge, UK.
  • Nagl K; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
  • Fritsch M; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Yong J; Department of Paediatrics, University of Cambridge, Cambridge, UK.
  • Metcalfe E; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
  • Schaeffer D; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
  • Fichelle M; Department of Paediatric Diabetes, Leeds Children's Hospital, Leeds, UK.
  • Schierloh U; Department of Paediatric Diabetes, Leeds Children's Hospital, Leeds, UK.
  • Thiele AG; Department of Pediatric Diabetes and Endocrinology, Clinique Pédiatrique, Centre Hospitalier, Luxembourg City, Luxembourg.
  • Abt D; Department of Pediatric Diabetes and Endocrinology, Clinique Pédiatrique, Centre Hospitalier, Luxembourg City, Luxembourg.
  • Kojzar H; Department of Pediatric Diabetes and Endocrinology, Clinique Pédiatrique, Centre Hospitalier, Luxembourg City, Luxembourg.
  • Mader JK; Division for Paediatric Diabetology, University of Leipzig, Leipzig, Germany.
  • Slegtenhorst S; Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.
  • Ashcroft N; Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
  • Wilinska ME; Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
  • Sibayan J; Department of Nutrition & Dietetics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Cohen N; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Kollman C; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Hofer SE; Department of Paediatrics, University of Cambridge, Cambridge, UK.
  • Fröhlich-Reiterer E; Jaeb Center for Health Research, Tampa, Florida.
  • Kapellen TM; Jaeb Center for Health Research, Tampa, Florida.
  • Acerini CL; Jaeb Center for Health Research, Tampa, Florida.
  • de Beaufort C; Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.
  • Campbell F; Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
  • Rami-Merhar B; Division for Paediatric Diabetology, University of Leipzig, Leipzig, Germany.
  • Hovorka R; Department of Paediatrics, University of Cambridge, Cambridge, UK.
Pediatr Diabetes ; 20(6): 794-799, 2019 09.
Article em En | MEDLINE | ID: mdl-31140654
ABSTRACT

OBJECTIVE:

To evaluate the experiences of families with very young children aged 1 to 7 years (inclusive) with type 1 diabetes using day-and-night hybrid closed-loop insulin delivery.

METHODS:

Parents/caregivers of 20 children aged 1 to 7 years with type 1 diabetes completed a closed-loop experience survey following two 3-week periods of unrestricted day-and-night hybrid closed-loop insulin therapy using Cambridge FlorenceM system at home. Benefits, limitations, and improvements of closed-loop technology were explored.

RESULTS:

Responders reported reduced burden of diabetes management, less time spent managing diabetes, and improved quality of sleep with closed-loop. Ninety percent of the responders felt less worried about their child's glucose control using closed-loop. Size of study devices, battery performance and connectivity issues were identified as areas for improvement. Parents/caregivers wished for more options to input information to the system such as temporary glucose targets.

CONCLUSIONS:

Parents/caregivers of very young children reported important quality of life benefits associated with using closed-loop, supporting adoption of this technology in this population.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Sistemas de Infusão de Insulina / Efeitos Psicossociais da Doença / Diabetes Mellitus Tipo 1 / Insulina Tipo de estudo: Clinical_trials Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Pediatr Diabetes Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Sistemas de Infusão de Insulina / Efeitos Psicossociais da Doença / Diabetes Mellitus Tipo 1 / Insulina Tipo de estudo: Clinical_trials Limite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Pediatr Diabetes Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido