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Genetic toxicology in silico protocol.
Hasselgren, Catrin; Ahlberg, Ernst; Akahori, Yumi; Amberg, Alexander; Anger, Lennart T; Atienzar, Franck; Auerbach, Scott; Beilke, Lisa; Bellion, Phillip; Benigni, Romualdo; Bercu, Joel; Booth, Ewan D; Bower, Dave; Brigo, Alessandro; Cammerer, Zoryana; Cronin, Mark T D; Crooks, Ian; Cross, Kevin P; Custer, Laura; Dobo, Krista; Doktorova, Tatyana; Faulkner, David; Ford, Kevin A; Fortin, Marie C; Frericks, Markus; Gad-McDonald, Samantha E; Gellatly, Nichola; Gerets, Helga; Gervais, Véronique; Glowienke, Susanne; Van Gompel, Jacky; Harvey, James S; Hillegass, Jedd; Honma, Masamitsu; Hsieh, Jui-Hua; Hsu, Chia-Wen; Barton-Maclaren, Tara S; Johnson, Candice; Jolly, Robert; Jones, David; Kemper, Ray; Kenyon, Michelle O; Kruhlak, Naomi L; Kulkarni, Sunil A; Kümmerer, Klaus; Leavitt, Penny; Masten, Scott; Miller, Scott; Moudgal, Chandrika; Muster, Wolfgang.
Afiliação
  • Hasselgren C; Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. Electronic address: hasselgren.catrin@gene.com.
  • Ahlberg E; Predictive Compound ADME & Safety, Drug Safety & Metabolism, AstraZeneca IMED Biotech Unit, Mölndal, Sweden.
  • Akahori Y; Chemicals Evaluation and Research Institute, 1-4-25 Kouraku, Bunkyo-ku, Tokyo, 112-0004, Japan.
  • Amberg A; Sanofi, R&D Preclinical Safety Frankfurt, Industriepark Hoechst, D-65926, Frankfurt am Main, Germany.
  • Anger LT; Sanofi, R&D Preclinical Safety Frankfurt, Industriepark Hoechst, D-65926, Frankfurt am Main, Germany.
  • Atienzar F; UCB BioPharma SPRL, Chemin du Foriest, B-1420 Braine-l'Alleud, Belgium.
  • Auerbach S; The National Institute of Environmental Health Sciences, Division of the National Toxicology Program, Research Triangle Park, NC, 27709, USA.
  • Beilke L; Toxicology Solutions Inc., San Diego, CA, USA.
  • Bellion P; DSM Nutritional Products, Kaiseraugst, Switzerland.
  • Benigni R; Alpha-PreTox, via G.Pascoli 1, 00184, Roma, Italy.
  • Bercu J; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
  • Booth ED; Syngenta, Product Safety Department, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK.
  • Bower D; Leadscope, Inc, 1393 Dublin Rd, Columbus, OH, 43215, USA.
  • Brigo A; Roche Pharmaceutical Research & Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070, Basel, Switzerland.
  • Cammerer Z; Janssen Research & Development, 1400 McKean Road, Spring House, PA, 19477, USA.
  • Cronin MTD; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, L3 3AF, UK.
  • Crooks I; British American Tobacco, Research and Development, Regents Park Road, Southampton, Hampshire, SO15 8TL, UK.
  • Cross KP; Leadscope, Inc, 1393 Dublin Rd, Columbus, OH, 43215, USA.
  • Custer L; Bristol-Myers Squibb, Drug Safety Evaluation, 1 Squibb Dr, New Brunswick, NJ, 08903, USA.
  • Dobo K; Pfizer Global Research & Development, 558 Eastern Point Road, Groton, CT, 06340, USA.
  • Doktorova T; Douglas Connect GmbH, Technology Park Basel, Hochbergerstrasse 60C, CH-4057, Basel / Basel-Stadt, Switzerland.
  • Faulkner D; Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 70A-1161A, Berkeley, CA, 947020, USA.
  • Ford KA; Global Blood Therapeutics, 171 Oyster Point Boulevard, South San Francisco, CA, 94080, USA.
  • Fortin MC; Jazz Pharmaceuticals, Inc., 200 Princeton South Corporate Center, Suite 180, Ewing, NJ, 08628, USA; Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, 170 Frelinghuysen Rd, Piscataway, NJ, 08855, USA.
  • Frericks M; BASF SE, 67056, Ludwigshafen, Germany.
  • Gad-McDonald SE; Gad Consulting Services, 4008 Barrett Drive, Suite 201, Raleigh, NC, 27609, USA.
  • Gellatly N; National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), Gibbs Building, 215 Euston Road, London, NW1 2BE, UK.
  • Gerets H; UCB BioPharma SPRL, Chemin du Foriest, B-1420, Braine-l'Alleud, Belgium.
  • Gervais V; Servier Group, 905 route de Saran, 45520, Gidy, France.
  • Glowienke S; Novartis Pharma AG, Pre-Clinical Safety, Werk Klybeck, CH, 4057, Basel, Switzerland.
  • Van Gompel J; Janssen Pharmaceutical Companies of Johnson & Johnson, 2340, Beerse, Belgium.
  • Harvey JS; GlaxoSmithKline Pre-Clinical Development, Park Road, Ware, Hertfordshire, SG12 0DP, UK.
  • Hillegass J; Bristol-Myers Squibb, Drug Safety Evaluation, 1 Squibb Dr, New Brunswick, NJ, 08903, USA.
  • Honma M; Division of Genetics and Mutagenesis, National Institute of Health Sciences, Kanagawa, 210-9501, Japan.
  • Hsieh JH; Kelly Government Solutions, Research Triangle Park, NC, 27709, USA.
  • Hsu CW; FDA Center for Drug Evaluation and Research, Silver Spring, MD, USA.
  • Barton-Maclaren TS; Existing Substances Risk Assessment Bureau, Health Canada, Ottawa, ON, K1A 0K9, Canada.
  • Johnson C; Leadscope, Inc, 1393 Dublin Rd, Columbus, OH, 43215, USA.
  • Jolly R; Toxicology Division, Eli Lilly and Company, Indianapolis, IN, USA.
  • Jones D; Medicines and Healthcare Products Regulatory Agency, 10 South Colonnade, Canary Wharf, London, E14 4PU, UK.
  • Kemper R; Vertex Pharmaceuticals Inc., Predictive and Investigative Safety Assessment, 50 Northern Ave, Boston, MA, USA.
  • Kenyon MO; Pfizer Global Research & Development, 558 Eastern Point Road, Groton, CT, 06340, USA.
  • Kruhlak NL; FDA Center for Drug Evaluation and Research, Silver Spring, MD, USA.
  • Kulkarni SA; Existing Substances Risk Assessment Bureau, Health Canada, Ottawa, ON, K1A 0K9, Canada.
  • Kümmerer K; Institute for Sustainable and Environmental Chemistry, Leuphana University Lüneburg, Scharnhorststraße 1/C13.311b, 21335, Lüneburg, Germany.
  • Leavitt P; Bristol-Myers Squibb, Drug Safety Evaluation, 1 Squibb Dr, New Brunswick, NJ, 08903, USA.
  • Masten S; The National Institute of Environmental Health Sciences, Division of the National Toxicology Program, Research Triangle Park, NC, 27709, USA.
  • Miller S; Leadscope, Inc, 1393 Dublin Rd, Columbus, OH, 43215, USA.
  • Moudgal C; Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Muster W; Roche Pharmaceutical Research & Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070, Basel, Switzerland.
Regul Toxicol Pharmacol ; 107: 104403, 2019 Oct.
Article em En | MEDLINE | ID: mdl-31195068
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Toxicologia / Modelos Teóricos / Mutagênicos Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Regul Toxicol Pharmacol Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa / Toxicologia / Modelos Teóricos / Mutagênicos Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Regul Toxicol Pharmacol Ano de publicação: 2019 Tipo de documento: Article