The Avidity Game: Selecting Natural-Born Killers.

Andoniou, Christopher E; Schuster, Iona S; Degli-Esposti, Mariapia A

Andoniou, Christopher E; Schuster, Iona S; Degli-Esposti, Mariapia A.

Afiliação

Andoniou CE; Infection and Immunity Program and Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia; Centre for Experimental Immunology, Lions Eye Institute, Perth, WA, Australia.
Schuster IS; Infection and Immunity Program and Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia; Centre for Experimental Immunology, Lions Eye Institute, Perth, WA, Australia.
Degli-Esposti MA; Infection and Immunity Program and Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia; Centre for Experimental Immunology, Lions Eye Institute, Perth, WA, Australia. Electronic address: mariapia.degli-esposti@monash.edu.

Immunity ; 50(6): 1337-1339, 2019 06 18.

Article em En | MEDLINE | ID: mdl-31216454

RESUMO

Natural killer (NK) cells display some features equivalent to those of adaptive immune effectors, but the molecular processes underlying these adaptive-like characteristics are just beginning to be defined. In this issue of Immunity, Adams et al. (2019) and Grassmann et al. (2019) report that avidity selection for Ly49H governs the expansion, differentiation, and function of NK cells after cytomegalovirus infection.

Assuntos

Infecções por Citomegalovirus; Diferenciação Celular; Humanos; Células Matadoras Naturais

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Citomegalovirus Limite: Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália

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