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Discovery of a highly specific and efficacious inhibitor of human carboxylesterase 2 by large-scale screening.
Song, Yun-Qing; Guan, Xiao-Qing; Weng, Zi-Miao; Wang, Ya-Qiao; Chen, Jing; Jin, Qiang; Fang, Sheng-Quan; Fan, Bin; Cao, Yun-Feng; Hou, Jie; Ge, Guang-Bo.
Afiliação
  • Song YQ; Translational Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine & Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 200473, China.
  • Guan XQ; Translational Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine & Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 200473, China.
  • Weng ZM; Translational Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine & Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 200473, China; Department of Biotechnology, College of Basic Medica
  • Wang YQ; Translational Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine & Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 200473, China.
  • Chen J; School of Life Science and Medicine, Dalian University of Technology, Panjin 124221, China.
  • Jin Q; Translational Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine & Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 200473, China.
  • Fang SQ; Department of Biotechnology, College of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China.
  • Fan B; Department of Biotechnology, College of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China.
  • Cao YF; Key Laboratory of Contraceptives and Devices Research, Shanghai Engineering Research Center of Reproductive Health Drug and Devices, Shanghai Institute of Planned Parenthood Research, Shanghai 200032, China.
  • Hou J; Department of Biotechnology, College of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China. Electronic address: houjie@dlmedu.edu.cn.
  • Ge GB; Translational Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine & Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 200473, China. Electronic address: geguangbo@dicp.ac.cn.
Int J Biol Macromol ; 137: 261-269, 2019 Sep 15.
Article em En | MEDLINE | ID: mdl-31260759

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carboxilesterase / Inibidores Enzimáticos / Descoberta de Drogas / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carboxilesterase / Inibidores Enzimáticos / Descoberta de Drogas / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China