Repurposed Oral Ribavirin for Respiratory Virus Infections Requires Pharmacokinetic-pharmacodynamic Dose Optimization.

de Zwart, Auke E S; Riezebos-Brilman, Annelies; Kerstjens, Huib A M; Verschuuren, Erik A M; Alffenaar, Jan-Willem C

de Zwart, Auke E S; Riezebos-Brilman, Annelies; Kerstjens, Huib A M; Verschuuren, Erik A M; Alffenaar, Jan-Willem C.

Afiliação

de Zwart AES; Department of Pulmonary Diseases and Tuberculosis, University Medical Centre Groningen, University of Groningen, The Netherlands.
Riezebos-Brilman A; Department of Medical Microbiology, University Medical Centre Utrecht, University of Utrecht, The Netherlands.
Kerstjens HAM; Department of Pulmonary Diseases and Tuberculosis, University Medical Centre Groningen, University of Groningen, The Netherlands.
Verschuuren EAM; Department of Pulmonary Diseases and Tuberculosis, University Medical Centre Groningen, University of Groningen, The Netherlands.
Alffenaar JC; University Faculty of Medicine and Health, School of Pharmacy, University of Sydney, Australia.

Clin Infect Dis ; 70(6): 1258, 2020 03 03.

Article em En | MEDLINE | ID: mdl-31271195

Assuntos

Antivirais; Transplante de Células-Tronco Hematopoéticas; Infecções por Vírus Respiratório Sincicial; Antivirais/uso terapêutico; Humanos; Infecções por Vírus Respiratório Sincicial/tratamento farmacológico; Ribavirina/uso terapêutico; Transplantados

Palavras-chave

paramyxovirus; pharmacokinetics; respiratory syncytial virus; ribavirin; transplantation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Infecções por Vírus Respiratório Sincicial / Transplante de Células-Tronco Hematopoéticas Limite: Humans Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda

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