Long-term recurrences of jaw osteoradionecrosis after apparent healing with the PENTOCLO protocol.
J Stomatol Oral Maxillofac Surg
; 121(3): 286-287, 2020 Jun.
Article
em En
| MEDLINE
| ID: mdl-31271892
ABSTRACT
Osteoradionecrosis of the jaws (ORNJ) is a late complication of head and neck irradiation estimated at around 3% of irradiated patients. The PENTO protocol (Pentoxyfilline and Tocopherol), with the eventual adjunction of Clodronate (PENTOCLO), showed interesting results even in advanced ORNJ. The current literature does not describe the long-term outcomes and particularly after the completion of the protocol. The PENTO or PENTOCLO protocol should be prescribed as a life-long treatment or the outcome should be monitored at least as long as the duration of the protocol after its end.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteorradionecrose
/
Neoplasias de Cabeça e Pescoço
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Revista:
J Stomatol Oral Maxillofac Surg
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
França