Dengue Mosaic Vaccines Enhance Cellular Immunity and Expand the Breadth of Neutralizing Antibody Against All Four Serotypes of Dengue Viruses in Mice.

Hou, Jue; Shrivastava, Shubham; Fraser, Christopher C; Loo, Hooi Linn; Wong, Lan Hiong; Ho, Victor; Fink, Katja; Ooi, Eng Eong; Chen, Jianzhu

Hou, Jue; Shrivastava, Shubham; Fraser, Christopher C; Loo, Hooi Linn; Wong, Lan Hiong; Ho, Victor; Fink, Katja; Ooi, Eng Eong; Chen, Jianzhu.

Afiliação

Hou J; Interdisciplinary Research Group in Infectious Diseases, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
Shrivastava S; Interdisciplinary Research Group in Infectious Diseases, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
Fraser CC; Interdisciplinary Research Group in Infectious Diseases, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
Loo HL; Interdisciplinary Research Group in Infectious Diseases, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
Wong LH; Interdisciplinary Research Group in Infectious Diseases, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
Ho V; Singapore Immunology Network, AStar, Singapore, Singapore.
Fink K; Singapore Immunology Network, AStar, Singapore, Singapore.
Ooi EE; Interdisciplinary Research Group in Infectious Diseases, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
Chen J; Emerging Infectious Diseases Program, Duke-NUS Graduate Medical School, Singapore, Singapore.

Front Immunol ; 10: 1429, 2019.

Article em En | MEDLINE | ID: mdl-31281322

Assuntos

Anticorpos Neutralizantes/imunologia; Anticorpos Antivirais/imunologia; Vacinas contra Dengue; Vírus da Dengue; Dengue; Epitopos de Linfócito T; Animais; Dengue/genética; Dengue/imunologia; Dengue/prevenção & controle; Vacinas contra Dengue/genética; Vacinas contra Dengue/imunologia; Vírus da Dengue/genética; Vírus da Dengue/imunologia; Epitopos de Linfócito T/genética; Epitopos de Linfócito T/imunologia; Feminino; Camundongos; Sorogrupo; Vacinas Sintéticas/genética; Vacinas Sintéticas/imunologia

Palavras-chave

T cell responses; cross-reactivity; dengue viruses; mosaic vaccine; neutralizing antibodies

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epitopos de Linfócito T / Dengue / Vírus da Dengue / Vacinas contra Dengue / Anticorpos Neutralizantes / Anticorpos Antivirais Limite: Animals Idioma: En Revista: Front Immunol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Singapura

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