Drp1 and RB interaction to mediate mitochondria-dependent necroptosis induced by cadmium in hepatocytes.

Zhang, Shili; Che, Lin; He, Chengyong; Huang, Jing; Guo, Nijun; Shi, Jiazhang; Lin, Yuchun; Lin, Zhongning

Zhang, Shili; Che, Lin; He, Chengyong; Huang, Jing; Guo, Nijun; Shi, Jiazhang; Lin, Yuchun; Lin, Zhongning.

Afiliação

Zhang S; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China.
Che L; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China.
He C; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China.
Huang J; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China.
Guo N; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China.
Shi J; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China.
Lin Y; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China. linych@xmu.edu.cn.
Lin Z; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, 361102, China. linzhn@xmu.edu.cn.

Cell Death Dis ; 10(7): 523, 2019 07 08.

Article em En | MEDLINE | ID: mdl-31285421

Assuntos

Cádmio/toxicidade; Dinaminas/metabolismo; Hepatócitos/metabolismo; Mitocôndrias/metabolismo; Necroptose/efeitos dos fármacos; Proteína do Retinoblastoma/metabolismo; Animais; Linhagem Celular; Hepatócitos/efeitos dos fármacos; Hepatócitos/ultraestrutura; Humanos; Masculino; Metformina/farmacologia; Camundongos Endogâmicos ICR; Mitocôndrias/efeitos dos fármacos; Ligação Proteica/efeitos dos fármacos; Regulação para Cima/efeitos dos fármacos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cádmio / Proteína do Retinoblastoma / Hepatócitos / Dinaminas / Necroptose / Mitocôndrias Limite: Animals / Humans / Male Idioma: En Revista: Cell Death Dis Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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