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PAN-AMPK Activation Improves Renal Function in a Rat Model of Progressive Diabetic Nephropathy.
Zhou, Xiaoyan; Muise, Eric S; Haimbach, Robin; Sebhat, Iyassu K; Zhu, Yonghua; Liu, Franklin; Souza, Sandra C; Kan, Yanqing; Pinto, Shirly; Kelley, David E; Hoek, Maarten.
Afiliação
  • Zhou X; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey xiaoyan_zhou@merck.com.
  • Muise ES; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey.
  • Haimbach R; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey.
  • Sebhat IK; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey.
  • Zhu Y; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey.
  • Liu F; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey.
  • Souza SC; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey.
  • Kan Y; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey.
  • Pinto S; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey.
  • Kelley DE; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey.
  • Hoek M; Department of Cardiometabolic Diseases (X.Z., R.H., Y.Z., F.L., S.C.S., Y.K., S.P., D.E.K., M.H.), Genetics and Pharmacogenomics (E.S.M.), and Medicinal Chemistry (I.K.S.), Merck & Co., Inc., Kenilworth, New Jersey mhoek@mazetx.com.
J Pharmacol Exp Ther ; 371(1): 45-55, 2019 10.
Article em En | MEDLINE | ID: mdl-31300612
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Piridinas / Nefropatias Diabéticas / Hipoglicemiantes / Imidazóis Tipo de estudo: Prognostic_studies Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Piridinas / Nefropatias Diabéticas / Hipoglicemiantes / Imidazóis Tipo de estudo: Prognostic_studies Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2019 Tipo de documento: Article