Airway hyperresponsiveness and late asthmatic responses.
Chest
; 94(1): 178-80, 1988 Jul.
Article
em En
| MEDLINE
| ID: mdl-3133162
Late inflammatory sequelae following allergen (and occupational low molecular weight sensitizing chemical) exposure, including the late asthmatic response and increased nonallergic airway responsiveness, are now felt to be more important in the pathogenesis of atopic allergic and occupational asthma than are the early bronchospastic responses. These late sequelae can be inhibited by sodium cromoglycate and by corticosteroids but not by bronchodilators. Recognition that allergic and occupational (and likely all forms of) asthma are inflammatory conditions underscores the rationale for the early use of anti-inflammatory therapeutic strategies in the management of asthma. Such "anti-inflammatory" therapeutic strategies include environmental control, sodium cromoglycate, and both inhaled and oral corticosteroids.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Espasmo Brônquico
/
Hipersensibilidade Tardia
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
En
Revista:
Chest
Ano de publicação:
1988
Tipo de documento:
Article
País de afiliação:
Canadá