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A novel epitope-presenting thermostable scaffold for the development of highly specific insulin-like growth factor-1/2 antibodies.
Peeß, Carmen; Scholz, Christian; Casagolda, David; Düfel, Hartmut; Gerg, Michael; Kowalewsky, Frank; Bocola, Marco; von Proff, Leopold; Goller, Sabine; Klöppel-Swarlik, Heidi; Hoppe, Alessandra; Schräml, Michael.
Afiliação
  • Peeß C; Antibody Development, Roche Diagnostics GmbH, 82377 Penzberg, Germany.
  • Scholz C; Protein Design, Roche Diagnostics GmbH, 82377 Penzberg, Germany.
  • Casagolda D; Enzyme & Protein Technologies, Roche Diagnostics GmbH, 82377 Penzberg, Germany.
  • Düfel H; Antibody Development, Roche Diagnostics GmbH, 82377 Penzberg, Germany.
  • Gerg M; Antibody Development, Roche Diagnostics GmbH, 82377 Penzberg, Germany.
  • Kowalewsky F; Antibody Development, Roche Diagnostics GmbH, 82377 Penzberg, Germany.
  • Bocola M; Lehrstuhl für Biotechnologie, RWTH Aachen University, 52074 Aachen, Germany.
  • von Proff L; Enzyme & Protein Technologies, Roche Diagnostics GmbH, 82377 Penzberg, Germany.
  • Goller S; Enzyme & Protein Technologies, Roche Diagnostics GmbH, 82377 Penzberg, Germany.
  • Klöppel-Swarlik H; Endocrinological Diseases III, Centralized and Point of Care, Roche Diagnostics GmbH, 82377 Penzberg, Germany.
  • Hoppe A; Endocrinological Diseases III, Centralized and Point of Care, Roche Diagnostics GmbH, 82377 Penzberg, Germany.
  • Schräml M; Enzyme & Protein Technologies, Roche Diagnostics GmbH, 82377 Penzberg, Germany. Electronic address: michael.schraeml@roche.com.
J Biol Chem ; 294(36): 13434-13444, 2019 09 06.
Article em En | MEDLINE | ID: mdl-31337703
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Temperatura / Fator de Crescimento Insulin-Like I / Fator de Crescimento Insulin-Like II / Anticorpos Monoclonais / Epitopos Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Temperatura / Fator de Crescimento Insulin-Like I / Fator de Crescimento Insulin-Like II / Anticorpos Monoclonais / Epitopos Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha