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The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors.
Bahjat, Mahnoush; de Wilde, Guus; van Dam, Tijmen; Maas, Chiel; Bloedjes, Timon; Bende, Richard J; van Noesel, Carel J M; Luijks, Dieuwertje M; Eldering, Eric; Kersten, Marie José; Guikema, Jeroen E J.
Afiliação
  • Bahjat M; Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam , Amsterdam , The Netherlands.
  • de Wilde G; Lymphoma and Myeloma Center Amsterdam (LYMMCARE) , Amsterdam , The Netherlands.
  • van Dam T; Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam , Amsterdam , The Netherlands.
  • Maas C; Lymphoma and Myeloma Center Amsterdam (LYMMCARE) , Amsterdam , The Netherlands.
  • Bloedjes T; Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam , Amsterdam , The Netherlands.
  • Bende RJ; Lymphoma and Myeloma Center Amsterdam (LYMMCARE) , Amsterdam , The Netherlands.
  • van Noesel CJM; Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam , Amsterdam , The Netherlands.
  • Luijks DM; Lymphoma and Myeloma Center Amsterdam (LYMMCARE) , Amsterdam , The Netherlands.
  • Eldering E; Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam , Amsterdam , The Netherlands.
  • Kersten MJ; Lymphoma and Myeloma Center Amsterdam (LYMMCARE) , Amsterdam , The Netherlands.
  • Guikema JEJ; Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam , Amsterdam , The Netherlands.
Cell Cycle ; 18(18): 2307-2322, 2019 09.
Article em En | MEDLINE | ID: mdl-31349760
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Dano ao DNA / Leucemia Mielogênica Crônica BCR-ABL Positiva / Proteínas de Fusão bcr-abl / Resistencia a Medicamentos Antineoplásicos / Ciclopentanos / Enzimas Ativadoras de Ubiquitina / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Cycle Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Dano ao DNA / Leucemia Mielogênica Crônica BCR-ABL Positiva / Proteínas de Fusão bcr-abl / Resistencia a Medicamentos Antineoplásicos / Ciclopentanos / Enzimas Ativadoras de Ubiquitina / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Cycle Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda