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Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aß Phagocytosis.
Miles, Luke A; Hermans, Stefan J; Crespi, Gabriela A N; Gooi, Jonathan H; Doughty, Larissa; Nero, Tracy L; Markulic, Jasmina; Ebneth, Andreas; Wroblowski, Berthold; Oehlrich, Daniel; Trabanco, Andrés A; Rives, Marie-Laure; Royaux, Ines; Hancock, Nancy C; Parker, Michael W.
Afiliação
  • Miles LA; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3056, Australia; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address: lmiles@s
  • Hermans SJ; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3056, Australia; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3010, Australia.
  • Crespi GAN; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3056, Australia; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3010, Australia.
  • Gooi JH; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3056, Australia; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3010, Australia.
  • Doughty L; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3056, Australia; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3010, Australia.
  • Nero TL; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3056, Australia; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3010, Australia.
  • Markulic J; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3056, Australia; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3010, Australia.
  • Ebneth A; Janssen Research & Development, a Division of Janssen Pharmaceutica N.V, 2340 Beerse, Belgium.
  • Wroblowski B; Janssen Research & Development, a Division of Janssen Pharmaceutica N.V, 2340 Beerse, Belgium.
  • Oehlrich D; Janssen Research & Development, a Division of Janssen Pharmaceutica N.V, 2340 Beerse, Belgium.
  • Trabanco AA; Neuroscience Medicinal Chemistry, Janssen Research & Development, 45007 Toledo, Spain.
  • Rives ML; Molecular and Cellular Pharmacology, Janssen Research & Development, LLC, La Jolla, CA 92121, USA.
  • Royaux I; Janssen Research & Development, a Division of Janssen Pharmaceutica N.V, 2340 Beerse, Belgium.
  • Hancock NC; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3056, Australia; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3010, Australia.
  • Parker MW; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3056, Australia; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address: mparker@
iScience ; 19: 110-118, 2019 Sep 27.
Article em En | MEDLINE | ID: mdl-31369984
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: IScience Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: IScience Ano de publicação: 2019 Tipo de documento: Article