Your browser doesn't support javascript.
loading
Treatment trends in oropharyngeal carcinoma: Surgical technology meets the epidemic.
Gal, T J; Slezak, Jon A; Kejner, Alexandra E; Chen, Quan; Huang, Bin.
Afiliação
  • Gal TJ; University of Kentucky, Department of Otolaryngology-Head and Neck Surgery, Lexington, KY, United States. Electronic address: tjgal2@uky.edu.
  • Slezak JA; University of Kentucky, Department of Otolaryngology-Head and Neck Surgery, Lexington, KY, United States.
  • Kejner AE; University of Kentucky, Department of Otolaryngology-Head and Neck Surgery, Lexington, KY, United States.
  • Chen Q; University of Kentucky, Markey Cancer Center, Lexington, KY, United States.
  • Huang B; University of Kentucky, Markey Cancer Center, Lexington, KY, United States; University of Kentucky, Department of Biostatistics, Lexington, KY, United States.
Oral Oncol ; 97: 62-68, 2019 10.
Article em En | MEDLINE | ID: mdl-31421473
OBJECTIVE: To characterize temporal trends in treatment patterns for oropharyngeal carcinoma, and to evaluate the emerging role of surgical therapy in the era of transoral robotic surgery (TORS). METHODS: Patients with oropharynx cancer between 2004 and 2016 identified using the National Cancer Database. Demographics and primary treatment modalities were obtained. Treatment was classified as surgery alone, surgery with radiation/chemotherapy, or primary radiation/chemotherapy. Annual distribution of cases treated by the various modalities was tabulated by site and early (I/II) versus late (III/IV) stage disease (AJCC 7th edition). The "TORS era" was defined as beginning in 2010. RESULTS: 149,534 patients were identified. The majority (56.8%) were treated with radiation ± chemotherapy. 53,069 patients had surgery as part of treatment, 72.6% (N = 38,533) of which received adjuvant therapy. 5293 TORS procedures were performed between 2010 and 2016 with trends away from open and other endoscopic procedures. Despite a 31.0% increase in the number of cases treated surgically from before TORS (2009) to 2016, the percentage of cases treated surgically decreased from 35.0% to 32.7%, with a 44.2% increase in non-surgical therapy. Increases in the percentage of patients treated surgically were observed for base of tongue tumors (24.3-25.2%) and early stage disease (59.9-62.2%). CONCLUSION: Despite the increase in the overall number of patients with oropharynx cancer, the percentages of patients treated surgically remains relatively stable. Notable increases were observed for base of tongue tumors and early stage disease.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma / Neoplasias Orofaríngeas Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Oral Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma / Neoplasias Orofaríngeas Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Oral Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article