Prediction of regulatory targets of alternative isoforms of the epidermal growth factor receptor in a glioblastoma cell line.

Weinholdt, Claus; Wichmann, Henri; Kotrba, Johanna; Ardell, David H; Kappler, Matthias; Eckert, Alexander W; Vordermark, Dirk; Grosse, Ivo

Weinholdt, Claus; Wichmann, Henri; Kotrba, Johanna; Ardell, David H; Kappler, Matthias; Eckert, Alexander W; Vordermark, Dirk; Grosse, Ivo.

Afiliação

Weinholdt C; Institute of Computer Science, Martin Luther University Halle-Wittenberg, Halle, Germany. claus.weinholdt@informatik.uni-halle.de.
Wichmann H; Department of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, Halle, Germany.
Kotrba J; Department of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, Halle, Germany.
Ardell DH; Institute for Molecular and Clinical Immunology, Otto-von-Guericke-University, Magdeburg, Germany.
Kappler M; Molecular Cell Biology, School of Natural Sciences, University of California, Merced, USA.
Eckert AW; Department of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, Halle, Germany.
Vordermark D; Department of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, Halle, Germany.
Grosse I; Department of Radiotherapy, Martin Luther University Halle-Wittenberg, Halle, Germany.

BMC Bioinformatics ; 20(1): 434, 2019 Aug 22.

Article em En | MEDLINE | ID: mdl-31438847

Assuntos

Processamento Alternativo/genética; Biologia Computacional/métodos; Receptores ErbB/genética; Glioblastoma/genética; Teorema de Bayes; Linhagem Celular Tumoral; Receptores ErbB/metabolismo; Humanos; Probabilidade; Isoformas de Proteínas/genética; Isoformas de Proteínas/metabolismo; Interferência de RNA; RNA Interferente Pequeno/metabolismo; Transdução de Sinais

Palavras-chave

Bayesian Gene Selection Criterion; Bayesian Information Criterion; EGFR; RNAi; Splice variants

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento Alternativo / Glioblastoma / Biologia Computacional / Receptores ErbB Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Bioinformatics Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha

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