Construction and Characterization of a PGN_0297 Mutant of Porphyromonas gingivalis: Evidence of the Contribution of PGN_0297 to Gingipain Activity.

Ono, Shintaro; Nakayama, Masaaki; Tachibana, Masato; Shahriar, Abu Saleh Muhammad; Heling, Wang; Takashiba, Shogo; Ohara, Naoya

Ono, Shintaro; Nakayama, Masaaki; Tachibana, Masato; Shahriar, Abu Saleh Muhammad; Heling, Wang; Takashiba, Shogo; Ohara, Naoya.

Afiliação

Ono S; Department of Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Nakayama M; Department of Oral Microbiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Tachibana M; Advanced Research Center for Oral and Craniofacial Sciences, Dental School, Okayama University, Okayama 700-8558, Japan.
Shahriar ASM; Department of Oral Microbiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Heling W; Department of Oral Microbiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Takashiba S; Department of Oral Microbiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.
Ohara N; Department of Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.

Acta Med Okayama ; 73(4): 315-323, 2019 Aug.

Article em En | MEDLINE | ID: mdl-31439954

Assuntos

Proteínas de Bactérias/metabolismo; Cisteína Endopeptidases Gingipaínas/metabolismo; Porphyromonas gingivalis/genética; Proteínas de Bactérias/genética; Linhagem Celular; Células Epiteliais/metabolismo; Células Epiteliais/microbiologia; Regulação da Expressão Gênica; Gengiva/citologia; Humanos; Mutação; Fosfatidilinositol 3-Quinases/metabolismo; Pigmentos Biológicos; Proteínas Proto-Oncogênicas c-akt/metabolismo

Palavras-chave

C-terminal domain; Porphyromonas gingivalis; gingipain; periodontitis; secretion system

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Porphyromonas gingivalis / Cisteína Endopeptidases Gingipaínas Limite: Humans Idioma: En Revista: Acta Med Okayama Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão

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