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Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade.
Georgiadis, Andrew; Durham, Jennifer N; Keefer, Laurel A; Bartlett, Bjarne R; Zielonka, Magdalena; Murphy, Derek; White, James R; Lu, Steve; Verner, Ellen L; Ruan, Finey; Riley, David; Anders, Robert A; Gedvilaite, Erika; Angiuoli, Sam; Jones, Siân; Velculescu, Victor E; Le, Dung T; Diaz, Luis A; Sausen, Mark.
Afiliação
  • Georgiadis A; Personal Genome Diagnostics, Baltimore, Maryland.
  • Durham JN; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Keefer LA; Personal Genome Diagnostics, Baltimore, Maryland.
  • Bartlett BR; Ludwig Center and Howard Hughes Medical Institute at Johns Hopkins, Baltimore, Maryland.
  • Zielonka M; Swim Across America Laboratory at Johns Hopkins, Baltimore, Maryland.
  • Murphy D; Personal Genome Diagnostics, Baltimore, Maryland.
  • White JR; Personal Genome Diagnostics, Baltimore, Maryland.
  • Lu S; Resphera Biosciences, Baltimore, Maryland.
  • Verner EL; Ludwig Center and Howard Hughes Medical Institute at Johns Hopkins, Baltimore, Maryland.
  • Ruan F; Personal Genome Diagnostics, Baltimore, Maryland.
  • Riley D; Personal Genome Diagnostics, Baltimore, Maryland.
  • Anders RA; Personal Genome Diagnostics, Baltimore, Maryland.
  • Gedvilaite E; Department of Pathology, Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins School of Medicine, Baltimore, Maryland.
  • Angiuoli S; Center for Molecular Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York.
  • Jones S; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.
  • Velculescu VE; Personal Genome Diagnostics, Baltimore, Maryland.
  • Le DT; Personal Genome Diagnostics, Baltimore, Maryland.
  • Diaz LA; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Sausen M; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Clin Cancer Res ; 25(23): 7024-7034, 2019 12 01.
Article em En | MEDLINE | ID: mdl-31506389
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Instabilidade de Microssatélites / Receptor de Morte Celular Programada 1 / DNA Tumoral Circulante / Antineoplásicos Imunológicos / Mutação / Neoplasias Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Instabilidade de Microssatélites / Receptor de Morte Celular Programada 1 / DNA Tumoral Circulante / Antineoplásicos Imunológicos / Mutação / Neoplasias Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article