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PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity.
LaFleur, Martin W; Nguyen, Thao H; Coxe, Matthew A; Miller, Brian C; Yates, Kathleen B; Gillis, Jacob E; Sen, Debattama R; Gaudiano, Emily F; Al Abosy, Rose; Freeman, Gordon J; Haining, W Nicholas; Sharpe, Arlene H.
Afiliação
  • LaFleur MW; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Nguyen TH; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Coxe MA; Evergrande Center for Immunological Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.
  • Miller BC; Division of Medical Sciences, Harvard Medical School, Boston, MA, USA.
  • Yates KB; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Gillis JE; Evergrande Center for Immunological Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.
  • Sen DR; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Gaudiano EF; Evergrande Center for Immunological Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.
  • Al Abosy R; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Freeman GJ; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Haining WN; Evergrande Center for Immunological Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.
  • Sharpe AH; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA.
Nat Immunol ; 20(10): 1335-1347, 2019 10.
Article em En | MEDLINE | ID: mdl-31527834
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Adenocarcinoma / Neoplasias do Colo / Linfócitos T CD8-Positivos / Células Progenitoras Linfoides / Proteína Tirosina Fosfatase não Receptora Tipo 2 / Imunoterapia / Coriomeningite Linfocítica / Vírus da Coriomeningite Linfocítica / Melanoma Limite: Animals Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Adenocarcinoma / Neoplasias do Colo / Linfócitos T CD8-Positivos / Células Progenitoras Linfoides / Proteína Tirosina Fosfatase não Receptora Tipo 2 / Imunoterapia / Coriomeningite Linfocítica / Vírus da Coriomeningite Linfocítica / Melanoma Limite: Animals Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos