MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-ß pathways.

Youn, Minyoung; Huang, Haigen; Chen, Cheng; Kam, Sharon; Wilkes, Mark C; Chae, Hee-Don; Sridhar, Kunju J; Greenberg, Peter L; Glader, Bertil; Narla, Anupama; Lin, Shuo; Sakamoto, Kathleen M

Youn, Minyoung; Huang, Haigen; Chen, Cheng; Kam, Sharon; Wilkes, Mark C; Chae, Hee-Don; Sridhar, Kunju J; Greenberg, Peter L; Glader, Bertil; Narla, Anupama; Lin, Shuo; Sakamoto, Kathleen M.

Afiliação

Youn M; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Huang H; Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA; and.
Chen C; Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA; and.
Kam S; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Wilkes MC; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Chae HD; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Sridhar KJ; Stanford University Cancer Center, Stanford, CA.
Greenberg PL; Stanford University Cancer Center, Stanford, CA.
Glader B; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Narla A; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
Lin S; Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA; and.
Sakamoto KM; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.

Blood Adv ; 3(18): 2751-2763, 2019 09 24.

Article em En | MEDLINE | ID: mdl-31540902

Assuntos

Eritropoese/fisiologia; Metaloproteinase 9 da Matriz/metabolismo; Fator de Crescimento Transformador beta/genética; Humanos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Metaloproteinase 9 da Matriz / Eritropoese Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Blood Adv Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá

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