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Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.
Lun, Melody P; Shannon, Morgan L; Keles, Sevgi; Reisli, Ismail; Luche, Nicole; Ryan, Douglas; Capuder, Kelly; Notarangelo, Luigi D; Lehtinen, Maria K.
Afiliação
  • Lun MP; Department of Pathology, Boston Children's Hospital, Boston, Massachusetts; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts.
  • Shannon ML; Department of Pathology, Boston Children's Hospital, Boston, Massachusetts.
  • Keles S; Department of Pediatric Allergy and Immunology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
  • Reisli I; Department of Pediatric Allergy and Immunology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
  • Luche N; Division of Immunology, Boston Children's Hospital, Boston, Massachusetts.
  • Ryan D; Division of Immunology, Boston Children's Hospital, Boston, Massachusetts.
  • Capuder K; Division of Immunology, Boston Children's Hospital, Boston, Massachusetts.
  • Notarangelo LD; Immune Deficiency Genetics Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland.
  • Lehtinen MK; Department of Pathology, Boston Children's Hospital, Boston, Massachusetts. Electronic address: maria.lehtinen@childrens.harvard.edu.
Am J Pathol ; 189(12): 2440-2449, 2019 12.
Article em En | MEDLINE | ID: mdl-31541646

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Apoptose / Anormalidades Craniofaciais / Modelos Animais de Doenças / DNA Ligase Dependente de ATP / Transtornos do Crescimento / Síndromes de Imunodeficiência / Microcefalia / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Pathol Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Apoptose / Anormalidades Craniofaciais / Modelos Animais de Doenças / DNA Ligase Dependente de ATP / Transtornos do Crescimento / Síndromes de Imunodeficiência / Microcefalia / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Pathol Ano de publicação: 2019 Tipo de documento: Article