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AMP-activated protein kinase inhibits MPP+-induced oxidative stress and apoptotic death of SH-SY5Y cells through sequential stimulation of Akt and autophagy.
Jovanovic-Tucovic, Maja; Harhaji-Trajkovic, Ljubica; Dulovic, Marija; Tovilovic-Kovacevic, Gordana; Zogovic, Nevena; Jeremic, Marija; Mandic, Milos; Kostic, Vladimir; Trajkovic, Vladimir; Markovic, Ivanka.
Afiliação
  • Jovanovic-Tucovic M; Institute of Medical and Clinical Biochemistry, University of Belgrade, Pasterova 2, 11000, Belgrade, Serbia.
  • Harhaji-Trajkovic L; Department of Neurophysiology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Despot Stefan Blvd. 142, 11000, Belgrade, Serbia.
  • Dulovic M; Institute of Neurogenetics, University of Lübeck, Maria-Goeppert-Straße 1, 23562, Lübeck, Germany.
  • Tovilovic-Kovacevic G; Department of Biochemistry, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Despot Stefan Blvd 142, 11000, Belgrade, Serbia.
  • Zogovic N; Department of Biochemistry, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Despot Stefan Blvd 142, 11000, Belgrade, Serbia.
  • Jeremic M; Institute of Medical and Clinical Biochemistry, University of Belgrade, Pasterova 2, 11000, Belgrade, Serbia.
  • Mandic M; Institute of Microbiology and Immunology, University of Belgrade, Dr Subotica 1, 11000, Belgrade, Serbia.
  • Kostic V; Clinic for Neurology CCS, University of Belgrade, Dr Subotica 6, 11000, Belgrade, Serbia.
  • Trajkovic V; Institute of Microbiology and Immunology, University of Belgrade, Dr Subotica 1, 11000, Belgrade, Serbia. Electronic address: vladimir.trajkovic@med.bg.ac.rs.
  • Markovic I; Institute of Medical and Clinical Biochemistry, University of Belgrade, Pasterova 2, 11000, Belgrade, Serbia. Electronic address: ivanka.markovic@med.bg.ac.rs.
Eur J Pharmacol ; 863: 172677, 2019 Nov 15.
Article em En | MEDLINE | ID: mdl-31542478
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / 1-Metil-4-fenilpiridínio / Apoptose / Estresse Oxidativo / Proteínas Proto-Oncogênicas c-akt / Proteínas Quinases Ativadas por AMP Limite: Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / 1-Metil-4-fenilpiridínio / Apoptose / Estresse Oxidativo / Proteínas Proto-Oncogênicas c-akt / Proteínas Quinases Ativadas por AMP Limite: Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2019 Tipo de documento: Article