Visible-Light-Driven Synthesis of 1,3,4-Trisubstituted Pyrroles from Aryl Azides.

Liu, Yang; Parodi, Adriano; Battaglioli, Simone; Monari, Magda; Protti, Stefano; Bandini, Marco

Liu, Yang; Parodi, Adriano; Battaglioli, Simone; Monari, Magda; Protti, Stefano; Bandini, Marco.

Afiliação

Liu Y; Department of Chemistry "G. Ciamician", Alma Mater Studiorum , University of Bologna , via Selmi 2 , 40126 Bologna , Italy.
Parodi A; Department of Chemistry "G. Ciamician", Alma Mater Studiorum , University of Bologna , via Selmi 2 , 40126 Bologna , Italy.
Battaglioli S; Department of Chemistry "G. Ciamician", Alma Mater Studiorum , University of Bologna , via Selmi 2 , 40126 Bologna , Italy.
Monari M; Department of Chemistry "G. Ciamician", Alma Mater Studiorum , University of Bologna , via Selmi 2 , 40126 Bologna , Italy.
Protti S; PhotoGreen Lab , V. Le Taramelli 10 , 27100 Pavia , Italy.
Bandini M; Department of Chemistry "G. Ciamician", Alma Mater Studiorum , University of Bologna , via Selmi 2 , 40126 Bologna , Italy.

Org Lett ; 21(19): 7782-7786, 2019 10 04.

Article em En | MEDLINE | ID: mdl-31545617

ABSTRACT

ABSTRACT

The synthesis of 1,3,4-trisubstituted pyrroles via visible-light mediated photoredox catalyzed condensation of arylazides and aldehydes has been reported herein. The methodology avoids the use of stoichiometric oxidants and provides the corresponding N-containing arenes in good yields (up to 78%) and mild conditions. Mechanistic rationale is provided via a dedicated and combined spectroscopic/experimental investigations.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Org Lett Assunto da revista: BIOQUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália

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