Lifelong consequences of brain injuries during development: From risk to resilience.
Front Neuroendocrinol
; 55: 100793, 2019 10.
Article
em En
| MEDLINE
| ID: mdl-31560884
ABSTRACT
Traumatic brain injuries in children represent a major public health issue and even relatively mild injuries can have lifelong consequences. However, the outcomes from these injuries are highly heterogeneous, with most individuals recovering fully, but a substantial subset experiencing prolonged or permanent disabilities across a number of domains. Moreover, brain injuries predispose individuals to other kinds of neuropsychiatric and somatic illnesses. Critically, the severity of the injury only partially predicts subsequent outcomes, thus other factors must be involved. In this review, we discuss the psychological, social, neuroendocrine, and autonomic processes that are disrupted following traumatic brain injury during development, and consider the mechanisms the mediate risk or resilience after traumatic brain injury in this vulnerable population.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos do Comportamento Social
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Sistema Nervoso Autônomo
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Transtornos de Estresse Pós-Traumáticos
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Sintomas Comportamentais
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Hormônio do Crescimento
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Lesões Encefálicas Traumáticas
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Desenvolvimento Humano
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Sistema Hipotálamo-Hipofisário
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Sistemas Neurossecretores
Tipo de estudo:
Etiology_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Front Neuroendocrinol
Ano de publicação:
2019
Tipo de documento:
Article