Intermittent hypoxia and hypercapnia induces inhibitor of nuclear factor-&#954;B kinase subunit ß-dependent atherosclerosis in pulmonary arteries.

Imamura, Toshihiro; Xue, Jin; Poulsen, Orit; Zhou, Dan; Karin, Michael; Haddad, Gabriel G

Intermittent hypoxia and hypercapnia induces inhibitor of nuclear factor-κB kinase subunit ß-dependent atherosclerosis in pulmonary arteries.

Imamura, Toshihiro; Xue, Jin; Poulsen, Orit; Zhou, Dan; Karin, Michael; Haddad, Gabriel G.

Afiliação

Imamura T; Department of Pediatrics, Division of Respiratory Medicine, University of California San Diego School of Medicine, La Jolla, California.
Xue J; Department of Pediatrics, Division of Respiratory Medicine, University of California San Diego School of Medicine, La Jolla, California.
Poulsen O; Department of Pediatrics, Division of Respiratory Medicine, University of California San Diego School of Medicine, La Jolla, California.
Zhou D; Department of Pediatrics, Division of Respiratory Medicine, University of California San Diego School of Medicine, La Jolla, California.
Karin M; Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, California.
Haddad GG; Department of Pathology, University of California San Diego School of Medicine, La Jolla, California.

Am J Physiol Regul Integr Comp Physiol ; 317(6): R763-R769, 2019 12 01.

Article em En | MEDLINE | ID: mdl-31618063

Assuntos

Aterosclerose/etiologia; Dióxido de Carbono/farmacologia; Hipercapnia/patologia; Hipóxia/patologia; Quinase I-kappa B/metabolismo; Oxigênio/farmacologia; Animais; Aterosclerose/metabolismo; Aterosclerose/patologia; Colesterol/sangue; Regulação da Expressão Gênica/efeitos dos fármacos; Quinase I-kappa B/genética; Camundongos; Camundongos Knockout; Proteínas Serina-Treonina Quinases; Artéria Pulmonar/patologia; Receptores de LDL/genética; Aumento de Peso; Quinase Induzida por NF-kappaB

Palavras-chave

atherosclerosis; intermittent hypoxia and hypercapnia; nuclear factor-κB; obstructive sleep apnea; pulmonary artery

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Dióxido de Carbono / Aterosclerose / Quinase I-kappa B / Hipercapnia / Hipóxia Limite: Animals Idioma: En Revista: Am J Physiol Regul Integr Comp Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google