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Impact of HIV-1 viremia or sexually transmitted infection on semen-derived anti-HIV-1 antibodies and the immunosuppressive capacity of seminal plasma.
Selva, Kevin J; Bavinton, Benjamin R; Grulich, Andrew E; Pazgier, Marzena; Kelleher, Anthony D; Kent, Stephen J; Parsons, Matthew S.
Afiliação
  • Selva KJ; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
  • Bavinton BR; The Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.
  • Grulich AE; The Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.
  • Pazgier M; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Kelleher AD; The Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.
  • Kent SJ; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
  • Parsons MS; Melbourne Sexual Health Centre and Infectious Disease Department, Alfred Health, Monash University Central Clinical School, Melbourne, Victoria, Australia.
Eur J Immunol ; 49(12): 2255-2258, 2019 12.
Article em En | MEDLINE | ID: mdl-31621073
ABSTRACT
Semen from HIV-1-infected men contains anti-HIV-1 antibodies and immunosuppressive factor(s). We assessed if suppression of viremia with antiretroviral therapy impacted seminal plasma immunosuppressive capacity or the Fc-dependent functions of seminal anti-HIV-1 antibodies. We also tested if active bacterial sexually transmitted infections altered the immunosuppressive capacity of seminal plasma.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sêmen / Viremia / Anticorpos Anti-HIV / Infecções por HIV / HIV-1 / Proteínas de Plasma Seminal / Antirretrovirais / Tolerância Imunológica Limite: Humans / Male Idioma: En Revista: Eur J Immunol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sêmen / Viremia / Anticorpos Anti-HIV / Infecções por HIV / HIV-1 / Proteínas de Plasma Seminal / Antirretrovirais / Tolerância Imunológica Limite: Humans / Male Idioma: En Revista: Eur J Immunol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália