Supramacromolecular injectable hydrogels by crystallization-driven self-assembly of carbohydrate-conjugated poly(2-isopropyloxazoline)s for biomedical applications.
J Mater Chem B
; 7(41): 6362-6369, 2019 10 23.
Article
em En
| MEDLINE
| ID: mdl-31642846
ABSTRACT
An approach for the preparation of self-healing and injectable hydrogels based on the crystallization-driven self-assembly of carbohydrate-conjugated poly(2-isopropyloxazoline)s is reported. Hydrogelation does not require any organic solvents, as the polymers dissolve in water below their lower critical solution temperatures. The transplanted hydrogels cause no significant foreign-body response. Considering the simplicity of the method and the biocompatibility of the resulting injectable hydrogels, crystallization-driven hydrogelation of poly(oxazoline)-based polymers may potentially be used in a wide range of biomedical applications.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxazóis
/
Carboidratos
/
Hidrogéis
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Tecnologia Biomédica
Idioma:
En
Revista:
J Mater Chem B
Ano de publicação:
2019
Tipo de documento:
Article