Propofol attenuates the adhesion of tumor and endothelial cells through inhibiting glycolysis in human umbilical vein endothelial cells.

Qi, Jie; Wu, Qichao; Zhu, Xuqin; Zhang, Shan; Chen, Xiangyuan; Chen, Wankun; Sun, Zhirong; Zhu, Minmin; Miao, Changhong

Qi, Jie; Wu, Qichao; Zhu, Xuqin; Zhang, Shan; Chen, Xiangyuan; Chen, Wankun; Sun, Zhirong; Zhu, Minmin; Miao, Changhong.

Afiliação

Qi J; Department of Anaesthesiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Wu Q; Department of Anaesthesiology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Zhu X; Department of Anaesthesiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Zhang S; Department of Anaesthesiology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Chen X; Department of Anaesthesiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Chen W; Department of Anaesthesia, Critical Care and Pain Medicine, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Sun Z; Department of Anaesthesiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Zhu M; Department of Anaesthesiology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Miao C; Department of Anaesthesiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.

Acta Biochim Biophys Sin (Shanghai) ; 51(11): 1114-1122, 2019 Nov 18.

Article em En | MEDLINE | ID: mdl-31650167

Assuntos

Carcinoma Hepatocelular/tratamento farmacológico; Adesão Celular/efeitos dos fármacos; Células Endoteliais da Veia Umbilical Humana/efeitos dos fármacos; Neoplasias Hepáticas/tratamento farmacológico; Propofol/farmacologia; Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina/metabolismo; Moléculas de Adesão Celular/metabolismo; Células Cultivadas; Glicólise/efeitos dos fármacos; Células Endoteliais da Veia Umbilical Humana/patologia; Humanos; Subunidade alfa do Fator 1 Induzível por Hipóxia/metabolismo

Palavras-chave

CaMKII; HIF-1α; glycolysis; propofol; tumor endothelial cell

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adesão Celular / Propofol / Carcinoma Hepatocelular / Células Endoteliais da Veia Umbilical Humana / Neoplasias Hepáticas Limite: Humans Idioma: En Revista: Acta Biochim Biophys Sin (Shanghai) Assunto da revista: BIOFISICA / BIOQUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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