Structural and computational examination of the <i>Arabidopsis</i> profilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.

Qiao, Zhu; Sun, He; Ng, Justin Tze Yang; Ma, Qianqian; Koh, Si Hui; Mu, Yuguang; Miao, Yansong; Gao, Yong-Gui

Structural and computational examination of the Arabidopsis profilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.

Qiao, Zhu; Sun, He; Ng, Justin Tze Yang; Ma, Qianqian; Koh, Si Hui; Mu, Yuguang; Miao, Yansong; Gao, Yong-Gui.

Afiliação

Qiao Z; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.
Sun H; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.
Ng JTY; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.
Ma Q; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.
Koh SH; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.
Mu Y; School of Biological Sciences, Nanyang Technological University, 637551 Singapore.
Miao Y; School of Biological Sciences, Nanyang Technological University, 637551 Singapore; School of Chemical and Biomedical Engineering, Nanyang Technological University, 637371 Singapore. Electronic address: yansongm@ntu.edu.sg.
Gao YG; School of Biological Sciences, Nanyang Technological University, 637551 Singapore; Institute of Molecular and Cell Biology, A*STAR (Agency for Science, Technology and Research), 138673 Singapore; Nanyang Technological University Institute of Structural Biology, Nanyang Technological University, 6397

J Biol Chem ; 294(49): 18650-18661, 2019 12 06.

Article em En | MEDLINE | ID: mdl-31653702

Assuntos

Citoesqueleto de Actina/metabolismo; Arabidopsis/metabolismo; Profilinas/metabolismo; Citoesqueleto de Actina/genética; Actinas/genética; Actinas/metabolismo; Arabidopsis/genética; Proteínas de Arabidopsis/genética; Proteínas de Arabidopsis/metabolismo; Immunoblotting; Proteínas dos Microfilamentos/genética; Proteínas dos Microfilamentos/metabolismo; Profilinas/genética; Proteínas de Saccharomyces cerevisiae/genética; Proteínas de Saccharomyces cerevisiae/metabolismo

Palavras-chave

actin; actin nucleation; conformational simulation; molecular docking; molecular dynamics; plant defense; profilin; profilin Poly-P complex; protein crystallization; structure biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citoesqueleto de Actina / Arabidopsis / Profilinas Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article

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