Loss of MYO5B expression deregulates late endosome size which hinders mitotic spindle orientation.

Leng, Changsen; Overeem, Arend W; Cartón-Garcia, Fernando; Li, Qinghong; Klappe, Karin; Kuipers, Jeroen; Cui, Yingying; Zuhorn, Inge S; Arango, Diego; van IJzendoorn, Sven C D

Leng, Changsen; Overeem, Arend W; Cartón-Garcia, Fernando; Li, Qinghong; Klappe, Karin; Kuipers, Jeroen; Cui, Yingying; Zuhorn, Inge S; Arango, Diego; van IJzendoorn, Sven C D.

Afiliação

Leng C; Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Overeem AW; Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Cartón-Garcia F; Group of Biomedical Research in Digestive Tract Tumors, CIBBIM-Nanomedicine, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.
Li Q; Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Klappe K; Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Kuipers J; Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Cui Y; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Zuhorn IS; Department of Biomedical Engineering, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Arango D; Group of Biomedical Research in Digestive Tract Tumors, CIBBIM-Nanomedicine, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.
van IJzendoorn SCD; Department of Biomedical Sciences of Cells and Systems, section Molecular Cell Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

PLoS Biol ; 17(11): e3000531, 2019 11.

Article em En | MEDLINE | ID: mdl-31682603

Assuntos

Endossomos/metabolismo; Cadeias Pesadas de Miosina/metabolismo; Miosina Tipo V/metabolismo; Fuso Acromático/metabolismo; Animais; Células CACO-2; Adesão Celular/fisiologia; Divisão Celular/fisiologia; Linhagem Celular; Membrana Celular/metabolismo; Citocinese/genética; Citocinese/fisiologia; Endossomos/genética; Células Epiteliais/metabolismo; Feminino; Células HEK293; Humanos; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Mitose/fisiologia; Cadeias Pesadas de Miosina/genética; Miosina Tipo V/genética; Proteínas rab de Ligação ao GTP/metabolismo; proteínas de unión al GTP Rab7

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endossomos / Cadeias Pesadas de Miosina / Miosina Tipo V / Fuso Acromático Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: PLoS Biol Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda

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