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Activation of the HIF1α/PFKFB3 stress response pathway in beta cells in type 1 diabetes.
Nomoto, Hiroshi; Pei, Lina; Montemurro, Chiara; Rosenberger, Madeline; Furterer, Allison; Coppola, Giovanni; Nadel, Brian; Pellegrini, Matteo; Gurlo, Tatyana; Butler, Peter C; Tudzarova, Slavica.
Afiliação
  • Nomoto H; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine at UCLA, University of California Los Angeles, 10833 Le Conte Avenue, 33-165 CHS, Los Angeles, CA, 90095-7073, USA.
  • Pei L; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine at UCLA, University of California Los Angeles, 10833 Le Conte Avenue, 33-165 CHS, Los Angeles, CA, 90095-7073, USA.
  • Montemurro C; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine at UCLA, University of California Los Angeles, 10833 Le Conte Avenue, 33-165 CHS, Los Angeles, CA, 90095-7073, USA.
  • Rosenberger M; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine at UCLA, University of California Los Angeles, 10833 Le Conte Avenue, 33-165 CHS, Los Angeles, CA, 90095-7073, USA.
  • Furterer A; Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Coppola G; Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Nadel B; Molecular Cell and Developmental Biology, College of Life Sciences, University of California Los Angeles, Los Angeles, CA, USA.
  • Pellegrini M; Molecular Cell and Developmental Biology, College of Life Sciences, University of California Los Angeles, Los Angeles, CA, USA.
  • Gurlo T; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine at UCLA, University of California Los Angeles, 10833 Le Conte Avenue, 33-165 CHS, Los Angeles, CA, 90095-7073, USA.
  • Butler PC; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine at UCLA, University of California Los Angeles, 10833 Le Conte Avenue, 33-165 CHS, Los Angeles, CA, 90095-7073, USA. pbutler@mednet.ucla.edu.
  • Tudzarova S; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine at UCLA, University of California Los Angeles, 10833 Le Conte Avenue, 33-165 CHS, Los Angeles, CA, 90095-7073, USA.
Diabetologia ; 63(1): 149-161, 2020 01.
Article em En | MEDLINE | ID: mdl-31720731
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfofrutoquinase-2 / Diabetes Mellitus Tipo 1 / Células Secretoras de Insulina / Subunidade alfa do Fator 1 Induzível por Hipóxia Limite: Adult / Aged80 / Animals / Child / Female / Humans / Male Idioma: En Revista: Diabetologia Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfofrutoquinase-2 / Diabetes Mellitus Tipo 1 / Células Secretoras de Insulina / Subunidade alfa do Fator 1 Induzível por Hipóxia Limite: Adult / Aged80 / Animals / Child / Female / Humans / Male Idioma: En Revista: Diabetologia Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos