Suppression of autoreactive T and B lymphocytes by anti-annexin A1 antibody in a humanized NSG murine model of systemic lupus erythematosus.

Mihaylova, N; Chipinski, P; Bradyanova, S; Velikova, T; Ivanova-Todorova, E; Chausheva, S; Herbáth, M; Kalinova, D; Prechl, J; Kyurkchiev, D; Tchorbanov, A I

Mihaylova, N; Chipinski, P; Bradyanova, S; Velikova, T; Ivanova-Todorova, E; Chausheva, S; Herbáth, M; Kalinova, D; Prechl, J; Kyurkchiev, D; Tchorbanov, A I.

Afiliação

Mihaylova N; Laboratory of Experimental Immunology, Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Chipinski P; Laboratory of Experimental Immunology, Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Bradyanova S; Laboratory of Experimental Immunology, Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Velikova T; Laboratory of Clinical Immunology, Department of Clinical Laboratory and Clinical Immunology, University Hospital St Ivan Rilski, Medical University of Sofia, Sofia, Bulgaria.
Ivanova-Todorova E; Laboratory of Clinical Immunology, Department of Clinical Laboratory and Clinical Immunology, University Hospital St Ivan Rilski, Medical University of Sofia, Sofia, Bulgaria.
Chausheva S; Laboratory of Experimental Immunology, Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Herbáth M; MTA-ELTE Immunology Research Group, Hungarian Academy of Sciences, Budapest, Hungary.
Kalinova D; Clinic of Rheumatology, University Hospital St Ivan Rilski, Sofia, Bulgaria.
Prechl J; MTA-ELTE Immunology Research Group, Hungarian Academy of Sciences, Budapest, Hungary.
Kyurkchiev D; Laboratory of Clinical Immunology, Department of Clinical Laboratory and Clinical Immunology, University Hospital St Ivan Rilski, Medical University of Sofia, Sofia, Bulgaria.
Tchorbanov AI; Laboratory of Experimental Immunology, Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.

Clin Exp Immunol ; 199(3): 278-293, 2020 03.

Article em En | MEDLINE | ID: mdl-31724735

Assuntos

Anexina A1/imunologia; Anticorpos/imunologia; Linfócitos B/imunologia; Modelos Animais de Doenças; Lúpus Eritematoso Sistêmico/imunologia; Linfócitos T/imunologia; Animais; Anexina A1/metabolismo; Anticorpos/farmacologia; Anticorpos Antinucleares/imunologia; Anticorpos Antinucleares/metabolismo; Apoptose/efeitos dos fármacos; Apoptose/imunologia; Linfócitos B/efeitos dos fármacos; Linfócitos B/metabolismo; Proliferação de Células/efeitos dos fármacos; Células Cultivadas; Humanos; Leucócitos Mononucleares/efeitos dos fármacos; Leucócitos Mononucleares/imunologia; Leucócitos Mononucleares/metabolismo; Lúpus Eritematoso Sistêmico/metabolismo; Ativação Linfocitária/imunologia; Camundongos Endogâmicos NOD; Camundongos Knockout; Camundongos SCID; Linfócitos T/efeitos dos fármacos; Linfócitos T/metabolismo

Palavras-chave

anti-annexin A1 antibody; humanized NOD-SCID mice; systemic lupus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Linfócitos T / Anexina A1 / Modelos Animais de Doenças / Lúpus Eritematoso Sistêmico / Anticorpos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Clin Exp Immunol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Bulgária

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