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Impact of Free-Breathing Phase-Contrast MRI on Decision-Making in Fontan Surgical Planning.
Wei, Zhenglun Alan; Trusty, Phillip M; Zhang, Yingnan; Tang, Elaine; Whitehead, Kevin K; Fogel, Mark A; Yoganathan, Ajit P.
Afiliação
  • Wei ZA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA.
  • Trusty PM; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA.
  • Zhang Y; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA.
  • Tang E; School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
  • Whitehead KK; Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Fogel MA; Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Yoganathan AP; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA. ajit.yoganathan@bme.gatech.edu.
J Cardiovasc Transl Res ; 13(4): 640-647, 2020 08.
Article em En | MEDLINE | ID: mdl-31732919
Fontan surgical planning ranks proposed surgical options according to their hemodynamics assessed by computational fluid dynamic (CFD) modeling. CFD commonly utilizes blood flow acquired under breath-holding (BH) conditions. Ignoring the free-breathing (FB) effect on blood flow waveforms may impact the ranking of surgical options. This study investigates such a potential impact by including ten Fontan patients who had blood flow acquisitions under both BH and FB conditions. A virtual surgery platform was used to generate two surgical options for each patient: (1) a traditional Fontan conduit and (2) a Y-graft. These options were ranked based on clinically relevant hemodynamic metrics: power loss (PL) and hepatic flow distribution (HFD). No difference was found in the ranking of options between using FB and BH flow acquisitions. The findings indicated that decision-making is not affected by the types of flow acquisition for Fontan surgical planning.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imageamento por Ressonância Magnética / Diagnóstico por Computador / Técnica de Fontan / Modelagem Computacional Específica para o Paciente / Tomada de Decisão Clínica / Cardiopatias Congênitas Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: J Cardiovasc Transl Res Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imageamento por Ressonância Magnética / Diagnóstico por Computador / Técnica de Fontan / Modelagem Computacional Específica para o Paciente / Tomada de Decisão Clínica / Cardiopatias Congênitas Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: J Cardiovasc Transl Res Assunto da revista: ANGIOLOGIA / CARDIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos