Molecular Evolution of <i>IDH</i> Wild-Type Glioblastomas Treated With Standard of Care Affects Survival and Design of Precision Medicine Trials: A Report From the EORTC 1542 Study.

Draaisma, Kaspar; Chatzipli, Aikaterini; Taphoorn, Martin; Kerkhof, Melissa; Weyerbrock, Astrid; Sanson, Marc; Hoeben, Ann; Lukacova, Slávka; Lombardi, Giuseppe; Leenstra, Sieger; Hanse, Monique; Fleischeuer, Ruth; Watts, Colin; McAbee, Joseph; Angelopoulos, Nicos; Gorlia, Thierry; Golfinopoulos, Vassilis; Kros, Johan M; Verhaak, Roel G W; Bours, Vincent; van den Bent, Martin J; McDermott, Ultan; Robe, Pierre A; French, Pim J

Molecular Evolution of IDH Wild-Type Glioblastomas Treated With Standard of Care Affects Survival and Design of Precision Medicine Trials: A Report From the EORTC 1542 Study.

Draaisma, Kaspar; Chatzipli, Aikaterini; Taphoorn, Martin; Kerkhof, Melissa; Weyerbrock, Astrid; Sanson, Marc; Hoeben, Ann; Lukacova, Slávka; Lombardi, Giuseppe; Leenstra, Sieger; Hanse, Monique; Fleischeuer, Ruth; Watts, Colin; McAbee, Joseph; Angelopoulos, Nicos; Gorlia, Thierry; Golfinopoulos, Vassilis; Kros, Johan M; Verhaak, Roel G W; Bours, Vincent; van den Bent, Martin J; McDermott, Ultan; Robe, Pierre A; French, Pim J.

Afiliação

Draaisma K; Erasmus University Medical Center, Rotterdam, the Netherlands.
Chatzipli A; Université de Liège, Liège, Belgium.
Taphoorn M; Wellcome Sanger Institute, Hinxton, United Kingdom.
Kerkhof M; Haaglanden Medisch Centrum, the Hague, the Netherlands.
Weyerbrock A; Haaglanden Medisch Centrum, the Hague, the Netherlands.
Sanson M; Universitätsklinikum Freiburg, Freiburg, Germany.
Hoeben A; Sorbonne Université, Paris, France.
Lukacova S; Maastricht University Medical Center, Maastricht, the Netherlands.
Lombardi G; Aarhus University Hospital, Aarhus, Denmark.
Leenstra S; Veneto Institute of Oncology-IRCCS, Padua, Italy.
Hanse M; Elizabeth-TweeSteden Hospital, Tilburg, the Netherlands.
Fleischeuer R; Elizabeth-TweeSteden Hospital, Tilburg, the Netherlands.
Watts C; Elizabeth-TweeSteden Hospital, Tilburg, the Netherlands.
McAbee J; University of Birmingham, Birmingham, United Kingdom.
Angelopoulos N; National Cancer Institute, Bethesda, MD.
Gorlia T; Wellcome Sanger Institute, Hinxton, United Kingdom.
Golfinopoulos V; European Organisation for Research and Treatment of Cancer, Brussels, Belgium.
Kros JM; European Organisation for Research and Treatment of Cancer, Brussels, Belgium.
Verhaak RGW; Erasmus University Medical Center, Rotterdam, the Netherlands.
Bours V; Jackson Lab for Genomic Medicine, Farmington, CT.
van den Bent MJ; Université de Liège, Liège, Belgium.
McDermott U; Erasmus University Medical Center, Rotterdam, the Netherlands.
Robe PA; Wellcome Sanger Institute, Hinxton, United Kingdom.
French PJ; Université de Liège, Liège, Belgium.

J Clin Oncol ; 38(1): 81-99, 2020 01 01.

Article em En | MEDLINE | ID: mdl-31743054

Assuntos

Neoplasias Encefálicas/terapia; Glioblastoma/genética; Glioblastoma/terapia; Isocitrato Desidrogenase/genética; Recidiva Local de Neoplasia/genética; Recidiva Local de Neoplasia/terapia; Medicina de Precisão/métodos; Adolescente; Adulto; Idoso; Antineoplásicos Alquilantes/administração & dosagem; Neoplasias Encefálicas/enzimologia; Neoplasias Encefálicas/genética; Estudos de Casos e Controles; Quimiorradioterapia; Protocolos Clínicos; Ensaios Clínicos como Assunto; Metilação de DNA; Metilases de Modificação do DNA/genética; Enzimas Reparadoras do DNA/genética; Evolução Molecular; Feminino; Glioblastoma/enzimologia; Humanos; Masculino; Pessoa de Meia-Idade; Recidiva Local de Neoplasia/enzimologia; Regiões Promotoras Genéticas; Temozolomida/administração & dosagem; Proteínas Supressoras de Tumor/genética; Adulto Jovem

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioblastoma / Medicina de Precisão / Isocitrato Desidrogenase / Recidiva Local de Neoplasia Tipo de estudo: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Oncol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda

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