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Smad7 in intestinal CD4+ T cells determines autoimmunity in a spontaneous model of multiple sclerosis.
Haupeltshofer, Steffen; Leichsenring, Teresa; Berg, Sarah; Pedreiturria, Xiomara; Joachim, Stephanie C; Tischoff, Iris; Otte, Jan-Michel; Bopp, Tobias; Fantini, Massimo C; Esser, Charlotte; Willbold, Dieter; Gold, Ralf; Faissner, Simon; Kleiter, Ingo.
Afiliação
  • Haupeltshofer S; St. Josef-Hospital, Department of Neurology, Ruhr-University Bochum, 44791 Bochum, Germany.
  • Leichsenring T; St. Josef-Hospital, Department of Neurology, Ruhr-University Bochum, 44791 Bochum, Germany.
  • Berg S; St. Josef-Hospital, Department of Neurology, Ruhr-University Bochum, 44791 Bochum, Germany.
  • Pedreiturria X; St. Josef-Hospital, Department of Neurology, Ruhr-University Bochum, 44791 Bochum, Germany.
  • Joachim SC; University Eye Clinic, Experimental Eye Research Institute, Ruhr-University Bochum, 44892 Bochum, Germany.
  • Tischoff I; Institut für Pathologie, Bergmannsheil, 44789 Bochum, Germany.
  • Otte JM; Department of Internal Medicine I, Klinikum Links der Weser, 28277 Bremen, Germany.
  • Bopp T; Institute for Immunology, Universitätsmedizin Mainz, 55131 Mainz, Germany.
  • Fantini MC; Research Center for Immunotherapy (FZI), Universitätsmedizin Mainz, 55131 Mainz, Germany.
  • Esser C; Department of Systems Medicine, University of Rome "Tor Vergata," 00133 Roma RM, Italy.
  • Willbold D; Leibniz-Institut für Umweltmedizinische Forschung, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
  • Gold R; Institut für Physikalische Biologie, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
  • Faissner S; Institute of Complex Systems (ICS-6), Forschungszentrum Jülich, 52425 Jülich, Germany.
  • Kleiter I; St. Josef-Hospital, Department of Neurology, Ruhr-University Bochum, 44791 Bochum, Germany.
Proc Natl Acad Sci U S A ; 116(51): 25860-25869, 2019 12 17.
Article em En | MEDLINE | ID: mdl-31796589
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Autoimunidade / Sistema Nervoso Central / Proteína Smad7 / Esclerose Múltipla Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Autoimunidade / Sistema Nervoso Central / Proteína Smad7 / Esclerose Múltipla Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha