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Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking.
Chen, Xiaoyu; Tasca, Francesca; Wang, Qian; Liu, Jin; Janssen, Josephine M; Brescia, Marcella D; Bellin, Milena; Szuhai, Karoly; Kenrick, Josefin; Frock, Richard L; Gonçalves, Manuel A F V.
Afiliação
  • Chen X; Leiden University Medical Center, Department of Cell and Chemical Biology, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Tasca F; Leiden University Medical Center, Department of Cell and Chemical Biology, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Wang Q; Leiden University Medical Center, Department of Cell and Chemical Biology, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Liu J; Leiden University Medical Center, Department of Cell and Chemical Biology, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Janssen JM; Leiden University Medical Center, Department of Cell and Chemical Biology, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Brescia MD; Leiden University Medical Center, Department of Cell and Chemical Biology, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Bellin M; Leiden University Medical Center, Department of Anatomy and Embryology, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Szuhai K; Leiden University Medical Center, Department of Cell and Chemical Biology, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Kenrick J; Stanford University School of Medicine, Division of Radiation and Cancer Biology, Department of Radiation Oncology, 269 Campus Dr. Stanford, CA 94305, USA.
  • Frock RL; Stanford University School of Medicine, Division of Radiation and Cancer Biology, Department of Radiation Oncology, 269 Campus Dr. Stanford, CA 94305, USA.
  • Gonçalves MAFV; Leiden University Medical Center, Department of Cell and Chemical Biology, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
Nucleic Acids Res ; 48(2): 974-995, 2020 01 24.
Article em En | MEDLINE | ID: mdl-31799604

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Desoxirribonuclease I / Sistemas CRISPR-Cas / Edição de Genes Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Desoxirribonuclease I / Sistemas CRISPR-Cas / Edição de Genes Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda