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The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis.
Tu, Jianghua; Park, Soohyun; Yu, Wangsheng; Zhang, Sheng; Wu, Ling; Carmon, Kendra; Liu, Qingyun J.
Afiliação
  • Tu J; Texas Therapeutics Institute and The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1825, Pressler St., Houston, Texas, USA.
  • Park S; Texas Therapeutics Institute and The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1825, Pressler St., Houston, Texas, USA.
  • Yu W; Texas Therapeutics Institute and The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1825, Pressler St., Houston, Texas, USA.
  • Zhang S; Texas Therapeutics Institute and The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1825, Pressler St., Houston, Texas, USA.
  • Wu L; Texas Therapeutics Institute and The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1825, Pressler St., Houston, Texas, USA.
  • Carmon K; Texas Therapeutics Institute and The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1825, Pressler St., Houston, Texas, USA.
  • Liu QJ; Texas Therapeutics Institute and The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, 1825, Pressler St., Houston, Texas, USA. Qingyun.liu@uth.tmc.edu.
Sci Rep ; 9(1): 18557, 2019 12 06.
Article em En | MEDLINE | ID: mdl-31811196
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ubiquitina-Proteína Ligases / Via de Sinalização Wnt / Carcinogênese / Proteína 1 Homóloga a MutL / Neoplasias Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ubiquitina-Proteína Ligases / Via de Sinalização Wnt / Carcinogênese / Proteína 1 Homóloga a MutL / Neoplasias Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos