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TAS-116 inhibits oncogenic KIT signalling on the Golgi in both imatinib-naïve and imatinib-resistant gastrointestinal stromal tumours.
Saito, Yurina; Takahashi, Tsuyoshi; Obata, Yuuki; Nishida, Toshirou; Ohkubo, Shuichi; Nakagawa, Fumio; Serada, Satoshi; Fujimoto, Minoru; Ohkawara, Tomoharu; Nishigaki, Takahiko; Sugase, Takahito; Koh, Masahiro; Ishida, Tomo; Tanaka, Koji; Miyazaki, Yasuhiro; Makino, Tomoki; Kurokawa, Yukinori; Nakajima, Kiyokazu; Yamasaki, Makoto; Hirota, Seiichi; Naka, Tetsuji; Mori, Masaki; Doki, Yuichiro.
Afiliação
  • Saito Y; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Takahashi T; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan. ttakahashi2@gesurg.med.osaka-u.ac.jp.
  • Obata Y; National Cancer Center Hospital, Tsukiji, Japan.
  • Nishida T; National Cancer Center Hospital, Tsukiji, Japan.
  • Ohkubo S; Taiho Pharmaceutical Co. Ltd, Tsukuba, Japan.
  • Nakagawa F; Taiho Pharmaceutical Co. Ltd, Tsukuba, Japan.
  • Serada S; Kochi Medical School Hospital, Nankoku, Japan.
  • Fujimoto M; Kochi Medical School Hospital, Nankoku, Japan.
  • Ohkawara T; Kochi Medical School Hospital, Nankoku, Japan.
  • Nishigaki T; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Sugase T; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Koh M; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Ishida T; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Tanaka K; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Miyazaki Y; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Makino T; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Kurokawa Y; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Nakajima K; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Yamasaki M; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Hirota S; Department of Surgical Pathology, Hyogo College of Medicine, Nishinomiya, Japan.
  • Naka T; Kochi Medical School Hospital, Nankoku, Japan.
  • Mori M; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
  • Doki Y; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Br J Cancer ; 122(5): 658-667, 2020 03.
Article em En | MEDLINE | ID: mdl-31857719
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Benzamidas / Proteínas Proto-Oncogênicas c-kit / Tumores do Estroma Gastrointestinal / Mesilato de Imatinib / Neoplasias Gastrointestinais / Complexo de Golgi Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Benzamidas / Proteínas Proto-Oncogênicas c-kit / Tumores do Estroma Gastrointestinal / Mesilato de Imatinib / Neoplasias Gastrointestinais / Complexo de Golgi Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Br J Cancer Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão