lncRNA JPX/miR-33a-5p/Twist1 axis regulates tumorigenesis and metastasis of lung cancer by activating Wnt/ß-catenin signaling.

Pan, Jinchang; Fang, Shuai; Tian, Haihua; Zhou, Chengwei; Zhao, Xiaodong; Tian, Hui; He, Jinxian; Shen, Weiyu; Meng, Xiaodan; Jin, Xiaofeng; Gong, Zhaohui

Pan, Jinchang; Fang, Shuai; Tian, Haihua; Zhou, Chengwei; Zhao, Xiaodong; Tian, Hui; He, Jinxian; Shen, Weiyu; Meng, Xiaodan; Jin, Xiaofeng; Gong, Zhaohui.

Afiliação

Pan J; Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo, 315211, China.
Fang S; Zhejiang Province Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo, 315211, China.
Tian H; Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo, 315211, China.
Zhou C; Zhejiang Province Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo, 315211, China.
Zhao X; Department of Biochemistry and Molecular Biology, Ningbo University School of Medicine, Ningbo, 315211, China.
Tian H; Zhejiang Province Key Laboratory of Pathophysiology, Ningbo University School of Medicine, Ningbo, 315211, China.
He J; Department of Laboratory Medicine, The Affiliated Ningbo Kangning Hospital of Ningbo University School of Medicine, Ningbo, 315201, China.
Shen W; Department of Thoracic Surgery, The Affiliated Hospital of Ningbo University School of Medicine, Ningbo, 315020, China.
Meng X; Department of Thoracic Surgery, The Affiliated Hospital of Ningbo University School of Medicine, Ningbo, 315020, China.
Jin X; Department of Thoracic Surgery, The Affiliated Ningbo Medical Center Lihuili Eastern Hospital of Ningbo University School of Medicine, Ningbo, 315048, China.
Gong Z; Department of Thoracic Surgery, The Affiliated Ningbo Medical Center Lihuili Eastern Hospital of Ningbo University School of Medicine, Ningbo, 315048, China.

Mol Cancer ; 19(1): 9, 2020 01 15.

Article em En | MEDLINE | ID: mdl-31941509

Assuntos

Adenocarcinoma de Pulmão/secundário; Neoplasias Pulmonares/patologia; MicroRNAs/genética; Proteínas Nucleares/metabolismo; RNA Longo não Codificante/genética; Proteína 1 Relacionada a Twist/metabolismo; Proteínas Wnt/metabolismo; beta Catenina/metabolismo; Adenocarcinoma de Pulmão/genética; Adenocarcinoma de Pulmão/metabolismo; Animais; Apoptose; Biomarcadores Tumorais; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/metabolismo; Carcinoma de Células Escamosas/secundário; Movimento Celular; Proliferação de Células; Feminino; Regulação Neoplásica da Expressão Gênica; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Pessoa de Meia-Idade; Invasividade Neoplásica; Proteínas Nucleares/genética; Prognóstico; Taxa de Sobrevida; Células Tumorais Cultivadas; Proteína 1 Relacionada a Twist/genética; Proteínas Wnt/genética; Ensaios Antitumorais Modelo de Xenoenxerto; beta Catenina/genética

Palavras-chave

Epithelial-mesenchymal transition; Long noncoding RNA; Lung cancer; Twist1; Wnt/ß-catenin signaling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / MicroRNAs / Proteínas Wnt / Beta Catenina / Proteína 1 Relacionada a Twist / RNA Longo não Codificante / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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