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Asparaginase induces selective dose- and time-dependent cytotoxicity, apoptosis, and reduction of NFκB expression in oral cancer cells.
Borges, Gabriel Álvares; Elias, Silvia Taveira; Araujo, Tassiana Souza De; Souza, Paula Monteiro; Nascimento-Filho, Carlos Henrique Viesi; Castilho, Rogerio M; Squarize, Cristiane H; Magalhães, Pérola de Oliveira; Guerra, Eliete Neves Silva.
Afiliação
  • Borges GÁ; Laboratory of Oral Histopathology, Faculty of Health Sciences, University of Brasilia, Brasilia, Brazil.
  • Elias ST; Epithelial Biology Laboratory, Department of Periodontics and Oral Medicine, Division of Oral Pathology Oral Radiology and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
  • Araujo TS; Laboratory of Oral Histopathology, Faculty of Health Sciences, University of Brasilia, Brasilia, Brazil.
  • Souza PM; Laboratory of Oral Histopathology, Faculty of Health Sciences, University of Brasilia, Brasilia, Brazil.
  • Nascimento-Filho CHV; Natural Products Laboratory, Faculty of Health Sciences, University of Brasilia, Brasilia, Brazil.
  • Castilho RM; Epithelial Biology Laboratory, Department of Periodontics and Oral Medicine, Division of Oral Pathology Oral Radiology and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
  • Squarize CH; Epithelial Biology Laboratory, Department of Periodontics and Oral Medicine, Division of Oral Pathology Oral Radiology and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
  • Magalhães PO; Epithelial Biology Laboratory, Department of Periodontics and Oral Medicine, Division of Oral Pathology Oral Radiology and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
  • Guerra ENS; Natural Products Laboratory, Faculty of Health Sciences, University of Brasilia, Brasilia, Brazil.
Clin Exp Pharmacol Physiol ; 47(5): 857-866, 2020 05.
Article em En | MEDLINE | ID: mdl-31943292
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asparaginase / Neoplasias da Língua / NF-kappa B / Apoptose / Carcinoma de Células Escamosas de Cabeça e Pescoço / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Exp Pharmacol Physiol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asparaginase / Neoplasias da Língua / NF-kappa B / Apoptose / Carcinoma de Células Escamosas de Cabeça e Pescoço / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Exp Pharmacol Physiol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Brasil