A New Alkaloid from the Aerial Parts of Bupleurum chinense DC.
Chem Biodivers
; 17(3): e1900697, 2020 Mar.
Article
em En
| MEDLINE
| ID: mdl-31943772
ABSTRACT
A new isoalloxazine alkaloid, named bupleurine A (1), along with five known compounds (2-6), were isolated from the aerial parts of Bupleurum chinense DC. The structure elucidation of the new alkaloid (1) was employed by combining NMR and HR-MS data with comparison of reference in the literature. Five known compounds (2-6) were isolated from Bupleurum genus for the first time. Additionally, their antiproliferative activities on HeLa cells were evaluated by MTT assay and IC50 of compounds 1 and 4-6 were below 10â
µm after treatment for 24â
h.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bupleurum
/
Componentes Aéreos da Planta
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Alcaloides
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Antineoplásicos Fitogênicos
Limite:
Humans
Idioma:
En
Revista:
Chem Biodivers
Assunto da revista:
BIOQUIMICA
/
QUIMICA
Ano de publicação:
2020
Tipo de documento:
Article