Pembrolizumab - emerging treatment of pulmonary sarcomatoid carcinoma: A case report.
World J Clin Cases
; 8(1): 97-102, 2020 Jan 06.
Article
em En
| MEDLINE
| ID: mdl-31970174
ABSTRACT
BACKGROUND:
Few studies have addressed the efficacy of pembrolizumab in pulmonary sarcomatoid carcinoma (PSC), a rare, previously rapidly fatal subtype of non-small-cell lung cancer. CASESUMMARY:
We report the case of a 69-year-old man presented with respiratory distress caused by a large left upper lung lobe mass diagnosed as PSC with programmed death-ligand 1 expressed on more than 50 percent of tumor cells. The patient was started on pembrolizumab and, after 5 cycles, there was a more than 80 percent decrease in the size of the tumor mass. Further decrease was seen at the end of 10 cycles. The patient has been tolerating pembrolizumab well, with no limiting side-effects. Fourteen months after first coming into the hospital, he remains asymptomatic.CONCLUSION:
Pembrolizumab appears as a viable emerging treatment for PSC.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
World J Clin Cases
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Estados Unidos