Incorporation of thiotepa in a reduced intensity conditioning regimen may improve engraftment after transplant for HLH.

Naik, Swati; Eckstein, Olive; Sasa, Ghadir; Heslop, Helen E; Krance, Robert A; Allen, Carl; Martinez, Caridad

Naik, Swati; Eckstein, Olive; Sasa, Ghadir; Heslop, Helen E; Krance, Robert A; Allen, Carl; Martinez, Caridad.

Afiliação

Naik S; Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital, Houston, TX, USA.
Eckstein O; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Sasa G; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Heslop HE; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Krance RA; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Allen C; Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital, Houston, TX, USA.
Martinez C; Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.

Br J Haematol ; 188(6): e84-e87, 2020 03.

Article em En | MEDLINE | ID: mdl-31989587

Assuntos

Antineoplásicos Alquilantes/uso terapêutico; Transplante de Células-Tronco Hematopoéticas/métodos; Linfo-Histiocitose Hemofagocítica/tratamento farmacológico; Linfo-Histiocitose Hemofagocítica/cirurgia; Tiotepa/uso terapêutico; Condicionamento Pré-Transplante/métodos; Adolescente; Antineoplásicos Alquilantes/farmacologia; Criança; Pré-Escolar; Feminino; Humanos; Lactente; Masculino; Tiotepa/farmacologia

Palavras-chave

hemophagocytic lymphohistiocytosis; reduced intensity conditioning; transplantation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiotepa / Transplante de Células-Tronco Hematopoéticas / Antineoplásicos Alquilantes / Condicionamento Pré-Transplante / Linfo-Histiocitose Hemofagocítica Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Br J Haematol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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