Soft tissue necrosis in patients treated with transoral robotic surgery and postoperative radiotherapy: preliminary results.
Tumori
; 106(6): 471-479, 2020 Dec.
Article
em En
| MEDLINE
| ID: mdl-31996091
ABSTRACT
OBJECTIVE:
Postoperative radiotherapy (PORT) is indicated in almost two-thirds of patients treated with transoral robotic surgery (TORS) for head and neck tumors. The aim of this study was to quantify the toxicity profile of patients treated with PORT after TORS in oropharyngeal and supraglottic laryngeal cancer focusing on soft tissue necrosis (STN).METHODS:
We retrospectively reviewed 28 patients. Acute and late toxicity were examined. Incidence and severity of STN were recorded.RESULTS:
No patient experienced acute grade 3 skin or mucosal toxicity; 1 patient had grade 3 dysphagia. At 12 months, no evaluated patient required enteral nutrition and 2 patients had tracheostomy. STN occurred in 4 (14%) patients 3 out of 4 (75%) patients with STN had diabetes, whereas 6 out of 13 (25%) patients without STN had diabetes (p = 0.05).CONCLUSION:
We found an acceptable toxicity profile of PORT performed after a TORS procedure. Diabetes mellitus might be a risk factor for STN.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
/
Radioterapia
/
Procedimentos Cirúrgicos Robóticos
/
Necrose
Tipo de estudo:
Diagnostic_studies
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Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Tumori
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Itália